Tetraplegia/Tetraparesis Clinical Trials

13 recruitingLast updated: May 13, 2026

There are 13 actively recruiting tetraplegia/tetraparesis clinical trials across 4 countries. Studies span Not Applicable, Early Phase 1. Top locations include New York, New York, United States, Baltimore, Maryland, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Tetraplegia/Tetraparesis Trials at a Glance

13 actively recruiting trials for tetraplegia/tetraparesis are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in New York, Baltimore, and Boston. Lead sponsors running tetraplegia/tetraparesis studies include Neuralink Corp, Columbia University, and Medical University of South Carolina.

Browse tetraplegia/tetraparesis trials by phase

Treatments under study

About Tetraplegia/Tetraparesis Clinical Trials

Looking for clinical trials for Tetraplegia/Tetraparesis? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tetraplegia/Tetraparesis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tetraplegia/Tetraparesis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Not Applicable

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

StrokeAmyotrophic Lateral SclerosisDysarthria+3 more
Paradromics2 enrolled3 locationsNCT07357428
Recruiting
Not Applicable

Virtual Peer Coaching in Manual Wheelchair Skills

Spinal Cord InjurySpinal Cord Injuries (SCI)Tetraplegia/Tetraparesis+2 more
University of Pittsburgh132 enrolled1 locationNCT06295146
Recruiting
Not Applicable

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

Spinal Cord Injuries (SCI)Amyotrophic Lateral Sclerosis(ALS)Muscular Dystrophies+6 more
Johns Hopkins University5 enrolled1 locationNCT07521930
Recruiting
Early Phase 1

MEP Up-conditioning to Target Corticospinal Plasticity

Spinal Cord InjuryTetraplegia/Tetraparesis
Medical University of South Carolina11 enrolled1 locationNCT06989905
Recruiting
Not Applicable

Precise Robotically IMplanted Brain-Computer InterfacE

QuadriplegiaAmyotrophic Lateral SclerosisCervical Spinal Cord Injury+3 more
Neuralink Corp15 enrolled2 locationsNCT06429735
Recruiting
Not Applicable

Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

Cervical Spinal Cord InjuryCervical MyelopathyTetraplegia/Tetraparesis
Columbia University36 enrolled2 locationsNCT06701422
Recruiting
Not Applicable

VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

QuadriplegiaStrokeAmyotrophic Lateral Sclerosis+4 more
Neuralink Corp6 enrolled1 locationNCT07224256
Recruiting
Not Applicable

GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

QuadriplegiaSpinal Cord InjuryMotor Neuron Disease+6 more
Neuralink Corp7 enrolled2 locationsNCT07127172
Recruiting
Not Applicable

Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia

Tetraplegia/Tetraparesis
Virginia Commonwealth University44 enrolled3 locationsNCT05423600
Recruiting
Not Applicable

UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

QuadriplegiaSpinal Cord InjuryMotor Neuron Disease+6 more
Neuralink Corp10 enrolled1 locationNCT06992596
Recruiting
Not Applicable

CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

QuadriplegiaSpinal Cord InjuryAmyotrophic Lateral Sclerosis(ALS)+4 more
Neuralink Corp6 enrolled1 locationNCT06700304
Recruiting
Early Phase 1

Spinal Cord Associative Plasticity Study

Cervical Spinal Cord InjuryCervical MyelopathyTetraplegia/Tetraparesis
Columbia University92 enrolled3 locationsNCT05163639
Recruiting

Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury

Cervical Spinal Cord InjuryTetraplegia/TetraparesisCervical Spinal Cord Paralysis+2 more
Stanford University10 enrolled1 locationNCT06541041