Phase 2 THA Clinical Trials

73 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 73 trials

Recruiting
Phase 2

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

Unresectable or Metastatic Hepatocellular CarcinomaChild-Pugh A Hepatocellular CarcinomaFailure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
CatalYm GmbH104 enrolled14 locationsNCT07219459
Recruiting
Phase 2

Role of Estrogen on Skeletal Outcomes in FHA

Bone DensityFHA (Functional Hypothalamic Amenorrhea)Bone Strength
University of Virginia150 enrolled2 locationsNCT07010146
Recruiting
Phase 2

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

GerminomaBasal Ganglia GerminomaDiabetes Insipidus+3 more
Children's Oncology Group240 enrolled114 locationsNCT06368817
Recruiting
Phase 2

A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

Functional Hypothalamic Amenorrhea (FHA)
Regeneron Pharmaceuticals34 enrolled10 locationsNCT07235917
Recruiting
Phase 1Phase 2

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

Beta-ThalassemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI)90 enrolled1 locationNCT07599176
Recruiting
Phase 1Phase 2

A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

Advanced Solid Tumors That Are MTAP Deficient
AstraZeneca334 enrolled21 locationsNCT06130553
Recruiting
Phase 2

Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea

Hypogonadotropic HypogonadismHypothalamic Amenorrhea
Stephanie B. Seminara, MD20 enrolled1 locationNCT07224438
Recruiting
Phase 2

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Beta-Thalassemia
Celgene99 enrolled26 locationsNCT04143724
Recruiting
Phase 2

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

methamphetamine abuseMethamphetamine DisordersMethamphetamine Intoxication
Clear Scientific, Inc.40 enrolled1 locationNCT06721494
Recruiting
Phase 1Phase 2

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Diamond-Blackfan AnemiaSickle Cell Anemiabeta thalassemia major
Paul Szabolcs5 enrolled1 locationNCT03653338
Recruiting
Phase 2Phase 3

Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo

Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 2

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

Hip arthroscopyTotal Hip Arthroplasty (THA)Total Knee Arthroplasty+1 more
Rush University Medical Center240 enrolled1 locationNCT07020312
Recruiting
Phase 2

A Phase 2 Study to Assess STP938 (Dencatistat) as a Monotherapy in Adults With High Risk Essential Thrombocythaemia - The VECTRA Trial

Essential Thrombocythaemia
Step Pharma, SAS50 enrolled14 locationsNCT06786234
Recruiting
Phase 2

Study of Olutasidenib and Temozolomide in HGG

Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled20 locationsNCT06161974
Recruiting
Phase 2

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Healthy Participants With Lower-than-average Mental Well-being
Robin Carhart-Harris, PhD, MA120 enrolled1 locationNCT06626139
Recruiting
Phase 2

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Sickle Cell DiseaseThalassemiaThalassemia (beta)
Memorial Sloan Kettering Cancer Center24 enrolled6 locationsNCT05736419
Recruiting
Phase 2

Glutide for Ending Methamphetamine

Methamphetamine Dependence
San Francisco Department of Public Health162 enrolled1 locationNCT07204249
Recruiting
Phase 2

Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin

AlbuminuriaSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)
University of Illinois at Chicago20 enrolled1 locationNCT07175051
Recruiting
Phase 2

Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease

Graves OrbitopathyGraves OphthalmopathyThyroid Eye Disease (TED)
The First Affiliated Hospital of Xiamen University8 enrolled1 locationNCT07547930
Recruiting
Phase 1Phase 2

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Acute Myeloid LeukemiaRecurrent Myelodysplastic SyndromeRefractory Myelodysplastic Syndrome+4 more
M.D. Anderson Cancer Center52 enrolled1 locationNCT04128748