Phase 4 Therapy Clinical Trials

47 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 47 trials

Recruiting
Phase 4

Study of the Effectiveness and Safety of Daunorubicin /Idarubicin ± Silibinin in Treating Newly Diagnosed AML (Non-M3).

Acute Myeloid LeukemiaChemotherapy EffectNewly Diagnosed
Fujian Medical University Union Hospital100 enrolled1 locationNCT07561892
Recruiting
Phase 4

Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia

Perioperative Respiratory Adverse EventsRespiratory HypersensitivityAnticholinergics+1 more
Sun Yat-sen University204 enrolled2 locationsNCT06624696
Recruiting
Phase 4

"Extended" (Alternate Day) Antipsychotic Dosing

Drug TherapySchizophrenia and Related DisordersAntipsychotic Agents+1 more
Centre for Addiction and Mental Health120 enrolled1 locationNCT04478838
Recruiting
Phase 4

Vitamin K for Perioperative Warfarin Management

Anticoagulant Therapy
University of Michigan20 enrolled1 locationNCT07515664
Recruiting
Phase 4

Jack Jumper Ant Venom Immunotherapy Long-term Effectiveness Investigation

ImmunotherapyAllergyVenom Allergy
Murdoch Childrens Research Institute100 enrolled3 locationsNCT06935890
Recruiting
Phase 4

Using a Steroid Mouthwash to Prevent Mouth Sores During Chemotherapy

Oral Mucositis Due to Chemotherapy
Woman's45 enrolled1 locationNCT07287826
Recruiting
Phase 4

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Nausea With Vomiting Chemotherapy-Induced
University of Illinois at Chicago90 enrolled1 locationNCT04150614
Recruiting
Phase 4

Ondansetron Orodispersible Film for Vomiting Prevention in Pediatric Radiotherapy

Pediatric CancerRadiotherapy-induced Nausea and Vomiting (RINV)
Chongqing University Cancer Hospital60 enrolled1 locationNCT07217600
Recruiting
Phase 4

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

CardiomyopathySudden Cardiac DeathHeart Failure With Reduced Ejection Fraction (HFrEF)+3 more
University of Rochester2,000 enrolled13 locationsNCT06964464
Recruiting
Phase 4

Tirzepatide in PWS, HO and GNSO

Prader-Willi SyndromeHypothalamic ObesityObesity/Therapy
Grace Kim36 enrolled3 locationsNCT06901245
Recruiting
Phase 4

Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage Closure

Left Atrial Appendage ClosureAspirinNonvalvular Atrial Fibrillation+2 more
OCEAN-SHD Study Group500 enrolled21 locationsNCT07125417
Recruiting
Phase 4

A Retrospective and Prospective Real-world Study of Molecular Typing in the Treatment of Advanced Thyroid Cancer

Advanced Thyroid Cancer Patients Who Received Target Therapy
Fudan University800 enrolled8 locationsNCT06195228
Recruiting
Phase 4

Comparison Of Reduced DAPT Followed by P2Y12 Inhibitor Monotherapy With Prasugrel vs stAndard Regimen in STEMI Patients

Dual Antiplatelet TherapyST Elevated Myocardial Infarction
Research Maatschap Cardiologen Rotterdam Zuid1,656 enrolled26 locationsNCT05491200
Recruiting
Phase 4

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

NSCLCLeptomeningeal MetastasisTyrosine Kinase Inhibitor+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology40 enrolled1 locationNCT07092202
Recruiting
Phase 4

Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity

ObesityWeight LossWeight Management+2 more
The Royal's Institute of Mental Health Research40 enrolled3 locationsNCT06809166
Not Yet Recruiting
Phase 4

Coagulation assessment of sublingual oestrogen (CASE) trial comparison of clotting profile and risk in transgender females on oral vs sublingual estrogen for gender affirming hormonal therapy

Gender affirming estrogen therapyVenous Thromboembolism (VTE)
Rita Upreti - Monash health30 enrolled1 locationACTRN12625000730404
Recruiting
Phase 4

Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study

SarcomaHyperbaric Oxygen Therapy
Duke University20 enrolled1 locationNCT03144206
Recruiting
Phase 4

Primary Tumor Ablation and Outcome in Metastatic Renal Cell Carcinoma Treated With Immunotherapy Combinations.

Renal Cell CancerRadiotherapyKidney Cancer+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS409 enrolled1 locationNCT06903312
Recruiting
Phase 4

Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis (HITs)

Antiplatelet TherapyHemorrhagic Infarction
Second Affiliated Hospital, School of Medicine, Zhejiang University294 enrolled1 locationNCT04624295
Recruiting
Phase 4

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Breast CancerHeart FailureBreast Diseases+10 more
Silesian Centre for Heart Diseases600 enrolled4 locationsNCT05465031