Early Phase 1 TIA Clinical Trials

12 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 112 of 12 trials

Recruiting
Early Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases

Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1

Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes

Interstitial Lung DiseaseSurfactant Dysfunction
Children's Hospital of Fudan University60 enrolled1 locationNCT04532346
Recruiting
Early Phase 1

Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions

Oral Potentially Malignant Lesions
Ain Shams University20 enrolled1 locationNCT06271564
Recruiting
Early Phase 1

[177Lu]Lu-AKIR001 First-in-human Study

Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital15 enrolled1 locationNCT06639191
Recruiting
Early Phase 1

PET Imaging Evaluation of [11C]SY08

Multiple System AtrophyDementia With Lewy BodiesParkinson's Disease+1 more
Massachusetts General Hospital40 enrolled1 locationNCT06098612
Recruiting
Early Phase 1

A Clinical Trial of SIBP-A16 Injection in Healthy Adults

Respiratory Syncytial Virus (RSV)
Shanghai Institute Of Biological Products140 enrolled1 locationNCT07106918
Recruiting
Early Phase 1

[18F]ACI-15916 PET in α-synucleinopathies

Parkinson's Disease (PD)Multiple System Atrophy (MSA)Dementia With Lewy Bodies (DLB)
AC Immune SA46 enrolled1 locationNCT06891703
Recruiting
Early Phase 1

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Interstitial CystitisBladder Pain SyndromeChronic Interstitial Cystitis
Wake Forest University Health Sciences30 enrolled1 locationNCT04734106
Recruiting
Early Phase 1

FAPI PET for Lung Fibrosis

PneumoconiosisRadiation PneumonitisInterstitial Lung Disease+4 more
University of California, Los Angeles30 enrolled1 locationNCT05365802
Recruiting
Early Phase 1

Study of 177Lu-LNC1004 Injection in FAP-positive Radioiodine-refractory Differentiated Thyroid Cancer

Radioiodine-refractory Differentiated Thyroid Cancer
Peking Union Medical College Hospital20 enrolled1 locationNCT06898437
Recruiting
Early Phase 1

[18F]ACI-19626 PET in TDP-43 Proteinopathies

Amyotrophic Lateral Sclerosis(ALS)Alzheimer's Disease(AD)Frontotemporal Dementia (FTD)+2 more
AC Immune SA45 enrolled1 locationNCT06891716
Recruiting
Early Phase 1

Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia

DementiaAlzheimer DiseaseProgressive Aphasia+3 more
University of Texas at Austin120 enrolled1 locationNCT06511752