Tobacco Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Tobacco clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Phase 4

Smoking Cessation and Menstrual Cycle Phase

Smoking CessationSubstance Use DisordersNicotine Dependence+2 more
Centre for Addiction and Mental Health1,200 enrolled1 locationNCT05515354
Recruiting
Not Applicable

ACT Lung Health Intervention: Phase Two

Smoking CessationSmoking BehaviorsSmoking, Tobacco+2 more
Dana-Farber Cancer Institute50 enrolled2 locationsNCT06945120
Recruiting
Not Applicable

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

ObesityHypertensionOverweight+4 more
Universidad Católica San Antonio de Murcia220 enrolled1 locationNCT07447362
Recruiting
Phase 2

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

Tobacco Use Disorder
VA Office of Research and Development50 enrolled1 locationNCT05723588
Recruiting
Phase 4

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

Tobacco Dependence
Johns Hopkins University30 enrolled1 locationNCT07220356
Recruiting
Not Applicable

Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

HypertensionType 2 Diabetes Mellitus (T2DM)Tobacco Smoking
Johns Hopkins Bloomberg School of Public Health2,070 enrolled1 locationNCT06740708
Recruiting
Not Applicable

Health Warnings and Counseling for Smoking Cessation

HypertensionNon Communicable Chronic DiseasesTobacco Cessation+1 more
Hitotsubashi University5,052 enrolled1 locationNCT07098065
Recruiting
Not Applicable

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

HIV InfectionTobacco-Related Carcinoma
AIDS Malignancy Consortium100 enrolled11 locationsNCT04949464
Recruiting
Not Applicable

Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes

HIVTobacco Use
Montefiore Medical Center400 enrolled1 locationNCT05642715
Recruiting
Not Applicable

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

Smoking CessationCancer PreventionHuman Immunodeficiency Virus (HIV)+4 more
Wake Forest University Health Sciences314 enrolled1 locationNCT06883097
Recruiting
Not Applicable

Smoking Cessation CM for Veterans With or at Risk for Cancer

Tobacco Use DisorderSubstance Use Disorder
VA Office of Research and Development108 enrolled1 locationNCT06432985
Recruiting
Not Applicable

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

COPDSmokingTobacco Use
Philip Morris Products S.A.290 enrolled111 locationsNCT07108166
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2

Tobacco Use DisorderAlcohol Use DisorderHIV
Yale University30 enrolled1 locationNCT06006143
Recruiting
Phase 3

V+PSF-M for Tobacco Cessation in HIV Care in India

Smoking CessationSmoking, TobaccoHuman Immunodeficiency Virus
University of Colorado, Denver400 enrolled2 locationsNCT05786547
Recruiting
Not Applicable

Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux

Barrett EsophagusObese PatientsTobacco Use+2 more
Louis Stokes VA Medical Center400 enrolled1 locationNCT06746623
Recruiting
Not Applicable

Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

Lung CarcinomaTobacco-Related Carcinoma
Ronald Myers822 enrolled1 locationNCT05679349
Recruiting
Not Applicable

Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)

Tobacco Use Cessation
University of Illinois at Chicago3,000 enrolled1 locationNCT04827420
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+8 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting

Analysis and Evaluation of Smoking Treatment With Cytisine

Moderate or Severe Tobacco Use Disorder
Regina Elena Cancer Institute65 enrolled1 locationNCT06439303
Recruiting
Not Applicable

Smoking Cessation Program for Adults With Type 2 Diabetes Mellitus (DiMe-SALUD2 Project)

Diabetes Mellitus, Type 2Tobacco Use Disorder
University of Seville90 enrolled1 locationNCT05885659