Tobacco Clinical Trials

2 recruiting

Tobacco Trials at a Glance

129 actively recruiting trials for tobacco are listed on ClinicalTrialsFinder across 6 cities in 30 countries. The largest study group is Not Applicable with 79 trials, with the heaviest enrollment activity in Columbus, San Francisco, and Baltimore. Lead sponsors running tobacco studies include Johns Hopkins University, Ohio State University Comprehensive Cancer Center, and University of California, San Francisco.

Treatments under study

About Tobacco Clinical Trials

Looking for clinical trials for Tobacco? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tobacco trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tobacco clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 129 trials

Recruiting
Phase 3

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

Opioid UseTobacco UsePolysubstance Abuse
Rutgers, The State University of New Jersey420 enrolled2 locationsNCT06033599
Recruiting
Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use DisorderNicotine DependenceCigarette Smoking
University of Oklahoma80 enrolled1 locationNCT05587361
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Not Applicable

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Cigarette SmokingTobacco ProductsElectronic Nicotine Delivery Systems
University of Chicago46 enrolled1 locationNCT06395415
Recruiting
Phase 2

Informing Oral Nicotine Pouch Regulations to Promote Public Health

Tobacco-Related Carcinoma
Ohio State University Comprehensive Cancer Center160 enrolled1 locationNCT06315881
Recruiting
Not Applicable

Trauma-Informed Care for Smoking Cessation for Pregnancy

Smoking CessationSmoking, CigaretteTobacco Use Cessation+4 more
University of California, San Francisco20 enrolled1 locationNCT07129590
Recruiting

Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt

Smoking (Tobacco) Addiction
University of Colorado, Denver250 enrolled1 locationNCT07553962
Recruiting
Not Applicable

Manipulating E-Cigarette Nicotine to Promote Public Health

Tobacco-Related Carcinoma
Ohio State University Comprehensive Cancer Center375 enrolled1 locationNCT06448351
Recruiting
Not Applicable

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

SmokingSmoking CessationSmoking, Tobacco+2 more
University of Virginia768 enrolled1 locationNCT05660525
Recruiting
Phase 2

Accelerated dTMS Smoking Cessation

Tobacco Use DisorderAddiction Nicotine
Waypoint Centre for Mental Health Care40 enrolled2 locationsNCT07292883
Recruiting
Not Applicable

RTMS Targets Neural Circuits for Smoking Cessation

Tobacco UseCigarette Smoking
Medical University of South Carolina64 enrolled2 locationsNCT04903028
Recruiting
Not Applicable

Health Warnings and Counseling for Smoking Cessation

HypertensionNon Communicable Chronic DiseasesTobacco Cessation+1 more
Hitotsubashi University3,400 enrolled1 locationNCT07098065
Recruiting
Not Applicable

Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)

Tobacco UseCigar Smoking
University of Oklahoma300 enrolled2 locationsNCT07162935
Recruiting
Not Applicable

Community-based Mobile-assisted Brief Intervention for Smoking Cessation

Smoking &Amp; Tobacco Cessation
National University of Singapore100 enrolled1 locationNCT07375459
Recruiting
Phase 1

Effect of Cannabis on E-Cigarette Use Behavior

Cannabis UseTobacco UseElectronic Cigarette Use
Johns Hopkins University100 enrolled1 locationNCT06609109
Recruiting
Not Applicable

Little Cigar Oxidants

Tobacco UseOxidative Stress
Milton S. Hershey Medical Center50 enrolled1 locationNCT06310187
Recruiting
Phase 2

Cannabidiol for Reducing Cigarette Use

Tobacco Use DisorderTobacco DependenceTobacco Smoking
University of California, Los Angeles120 enrolled1 locationNCT06218056
Recruiting
Not Applicable

Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients

AnxietyTobacco Use DisorderNicotine Dependence+2 more
Chiao-Chiao Liao60 enrolled1 locationNCT07466875
Recruiting
Not Applicable

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

Substance Use DisordersTobacco Use
Medical University of South Carolina240 enrolled4 locationsNCT06922617
Recruiting
Phase 3

Cannabis-Tobacco Co-Use Treatment Study

Tobacco Use DisorderTobacco Use CessationCannabis Use+2 more
Medical University of South Carolina200 enrolled1 locationNCT06883162