Phase 1 Tolerance Clinical Trials
5 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–5 of 5 trials
Recruiting
Phase 1Phase 2
Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor
Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Phase 1Phase 2
Immune Tolerance Induction After Liver Transplantation
Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
Chronic Kidney DiseasesEnd-stage Kidney DiseaseKidney Transplant Failure and Rejection+1 more
University of California, Los Angeles10 enrolled1 locationNCT05525507
Recruiting
Phase 1Phase 2
Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.
Platinum Resistant Ovarian CancerPlatinum-Resistant Fallopian Tube CarcinomaPlatinum-Resistant Primary Peritoneal Carcinoma+6 more
TILT Biotherapeutics Ltd.29 enrolled3 locationsNCT05271318
Recruiting
Phase 1
Effect of Fucoidan on glucose control and markers of cardiometabolic health after chronic dosing
Insulin Resistance/sensitivityHypercholesterolaemiaObesity+3 more
University of Tasmania.80 enrolled1 locationACTRN12614000495628