Phase 2 Tolerance Clinical Trials

12 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 112 of 12 trials

Recruiting
Phase 2

Efficacy and Safety of Oral Controlled-release Nicotinic Acid (CIR-NA) for the Remission of Prediabetes. (CONCEPT)

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
University Hospital Schleswig-Holstein390 enrolled2 locationsNCT07286747
Recruiting
Phase 1Phase 2

Immune Tolerance Induction After Liver Transplantation

Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 1Phase 2

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Phase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621
Recruiting
Phase 2Phase 3

Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes

Pregnancy ComplicationsGlucose Metabolism DisordersDiabetes, Gestational+1 more
Jaeb Center for Health Research30 enrolled5 locationsNCT06535789
Recruiting
Phase 2

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Cystic FibrosisDiabetesPancreatic Insufficiency+1 more
University of Pennsylvania30 enrolled2 locationsNCT04731272
Not Yet Recruiting
Phase 2

Dose-response study of probiotics in sick term and late preterm infants: the PRINS-2 trial

feed intolerancegastroschisishypoxic ischaemic encephalopathy+1 more
Child and Adolescent health Service108 enrolled1 locationACTRN12624001428550
Recruiting
Phase 2

Elucidating the Effects of Tocotrienol rich Vitamin E on Metabolic Biomarkers in a Pre-diabetes Population in Malaysia.

PrediabetesImpaired Glucose ToleranceImpaired fasting glucose
Monash University Malaysia80 enrolled2 locationsACTRN12622000256774
Completed
Phase 2

Investigating the effect of a soluble seaweed dietary fibre on gut, metabolic and skin health.

Keratoderma/psoriatic skin conditionIncreased Chronic InflammationImpaired Glucose Tolerance and Insulin resistance+2 more
University of Wollongong80 enrolled1 locationACTRN12617001010381
Completed
Phase 2Phase 3

Clinical trial of a Chinese herbal medicine for the treatment of prediabetes and mild diabetes

Mild diabetes defined as those with diabetes diagnosed within 5 yrs of enrolment in the clinical trial, diet and exercise controlled and not taking any medications.Impaired glucose tolerance defined as having a fasting blood glucose <7.8 mmol and a 2 hour post prandial blood glucose >7.8 but <11.00
Xiyuan Hospital100 enrolled1 locationACTRN12612000128897
Withdrawn
Phase 2

Does adjunctive therapy with Minocycline improve pain and opioid effectiveness in complex lower limb trauma? - A prospective randomised controlled trial.

Neuropathic Pain in Complex Lower Limb TraumaGlial activation by opioids acting at TLR4 receptors in Complex Lower Limb Trauma.Opioid tolerance in Complex Lower Limb Trauma.
Dr David Lindholm90 enrolled1 locationACTRN12611000118909
Recruiting
Phase 2

Evaluation of Anxiolysis and Pain Associated with Retrobulbar Eye Block for Cataract Surgery : Melatonin versus Gabapentin ( A randomized, double-blind, placebo-controlled study)

Tolerance of retrobulbar injection and comfort during the surgical procedureanxiety during performance retrobulbar block and cataract surgerypain during performance retrobulbar block and cataract surgery
Qazvin university of medical science90 enrolled1 locationACTRN12610000727044