Tolerance Clinical Trials

6 recruiting

Tolerance Trials at a Glance

76 actively recruiting trials for tolerance are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 45 trials, with the heaviest enrollment activity in Boston, Aurora, and Basel. Lead sponsors running tolerance studies include Georgia State University, Oregon Health and Science University, and Sydney Cancer Centre.

Browse tolerance trials by phase

Treatments under study

About Tolerance Clinical Trials

Looking for clinical trials for Tolerance? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tolerance trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tolerance clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 76 trials

Recruiting
Not Applicable

Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.

Traumatic Brain InjuryNeurocritical CareEnteral Feeding Intolerance
Tang-Du Hospital100 enrolled1 locationNCT07092423
Recruiting
Not Applicable

FMT for Lung and Associated-organ Rescue Efficacy in ARDS Patients

Lung InfectionMicrobial ColonizationFood Intolerance Syndromes
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology150 enrolled1 locationNCT06970262
Recruiting
Not Applicable

Oral Nutritional Supplement in Adults With or at Risk of Malnutrition

Gastrointestinal Tolerance
Abbott Nutrition25 enrolled3 locationsNCT07426406
Recruiting

Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients

Critical IllnessEnteral Nutrition FeedingMachine Learning+2 more
Ruijin Hospital500 enrolled1 locationNCT07521111
Recruiting
Not Applicable

Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals

Skin CancerHeat Tolerance
University of Thessaly80 enrolled2 locationsNCT07510061
Recruiting
Phase 2

Efficacy and Safety of Oral Controlled-release Nicotinic Acid (CIR-NA) for the Remission of Prediabetes. (CONCEPT)

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
University Hospital Schleswig-Holstein390 enrolled2 locationsNCT07286747
Recruiting
Not Applicable

Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

Enteral Feeding Intolerance
Boston Children's Hospital45 enrolled1 locationNCT04900597
Recruiting
Not Applicable

Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation

Cognitive DysfunctionPrediabetes (Insulin Resistance, Impaired Glucose Tolerance)Overweight (BMI > 25)+3 more
Leeds Beckett University70 enrolled1 locationNCT07073781
Recruiting
Not Applicable

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Arterial StiffnessBody CompositionAdult+9 more
Georgia State University30 enrolled1 locationNCT06735651
Recruiting
Not Applicable

Peanuts for Cardiometabolic, Brain, and Intestinal Health

AdultPrediabetesCognition+5 more
Georgia State University72 enrolled1 locationNCT06867198
Recruiting
Not Applicable

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

Obstructive Sleep ApneaDown SyndromeTolerance+3 more
University of Michigan40 enrolled1 locationNCT05527652
Recruiting
Phase 1Phase 2

Immune Tolerance Induction After Liver Transplantation

Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting

Mechanisms of Maternal Immune Tolerance in Early Pregnancy

PregnancyImmune Tolerance
University Hospital, Basel, Switzerland100 enrolled1 locationNCT07297394
Recruiting
Not Applicable

Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism

Quality of Life (QOL)Exercise TherapyAnxiety Depression+7 more
Insel Gruppe AG, University Hospital Bern160 enrolled5 locationsNCT07143539
Recruiting
Early Phase 1

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, ToleranceOral vs Vaporized THCAbuse Liability
Yale University20 enrolled1 locationNCT05906511
Recruiting
Not Applicable

Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults

FrailtyAgingExercise Tolerance+1 more
Scott Silveira40 enrolled1 locationNCT07144527
Recruiting
Not Applicable

Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes

Gestational Diabetes Mellitus in PregnancyGlucose Intolerance During PregnancyNon-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
George Washington University324 enrolled1 locationNCT06548828
Recruiting
Not Applicable

Does the Thickness of the Gastrostomy Affect the Incidence of Complications? A Prospective Randomized Single-Center Study in Children

Food IntoleranceGastrostomy ComplicationsGranuloma+1 more
Therese Hössjer200 enrolled1 locationNCT07300865
Recruiting
Not Applicable

Bedside Observation by Clinical Ultrasound for Stomach Expansion

Enteral Feeding Intolerance
Centre Hospitalier Saint Joseph Saint Luc de Lyon150 enrolled1 locationNCT07312890
Recruiting

Predictive Factors of Response to Phase II Cardiac Rehabilitation in Heart Failure With Reduced Ejection Fraction

Exercise TrainingHFrEF - Heart Failure With Reduced Ejection FractionCardiac Rehabilitation+3 more
Centre Hospitalier de Corbie62 enrolled1 locationNCT07164911