Tolerance Clinical Trials

102 recruitingLast updated: June 18, 2026

There are 102 actively recruiting tolerance clinical trials across 27 countries. Studies span Not Applicable, Phase 2, Phase 1, Early Phase 1, Phase 3, Phase 4. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Aurora, Colorado, United States. Updated daily from ClinicalTrials.gov.


Tolerance Trials at a Glance

102 actively recruiting trials for tolerance are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 64 trials, with the heaviest enrollment activity in Boston, New York, and Aurora. Lead sponsors running tolerance studies include Georgia State University, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, and Oregon Health and Science University.

Browse tolerance trials by phase

Treatments under study

About Tolerance Clinical Trials

Looking for clinical trials for Tolerance? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tolerance trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tolerance clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 102 trials

Recruiting
Not Applicable

Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism

Quality of Life (QOL)Exercise TherapyAnxiety Depression+7 more
Insel Gruppe AG, University Hospital Bern160 enrolled6 locationsNCT07143539
Recruiting
Not Applicable

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

Feasibility, Tolerance and Safety of VR Delivery in an Adult ICU
Milton S. Hershey Medical Center30 enrolled1 locationNCT07649876
Recruiting
Early Phase 1

Tolerance Through Mixed Chimerism (Sip-Tego)

Kidney FailureTransplant Recipient (Kidney)Immunosuppresion+2 more
Tatsuo Kawai, MD, PhD12 enrolled1 locationNCT06972069
Recruiting
Phase 3

Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes

Glucose Intolerance After a Recent History of Gestational Diabetes
Universitaire Ziekenhuizen KU Leuven252 enrolled13 locationsNCT05569772
Recruiting
Not Applicable

Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes

PrediabetesPrediabetes (Insulin Resistance, Impaired Glucose Tolerance)Prediabetes or Diabetes
Shifa International Hospital105 enrolled1 locationNCT07618663
Recruiting
Not Applicable

Milk for Diabetes Prevention

Lactose intoleranceDiabetes Mellitus, Type 2Pre-diabetes+2 more
Albert Einstein College of Medicine40 enrolled1 locationNCT06513026
Recruiting
Not Applicable

Test of Target Engagement of Ambiguity Aversion

Depression, AnxietyAnxietyIntolerance of Uncertainty+1 more
Northwestern University140 enrolled1 locationNCT06962527
Recruiting
Not Applicable

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

SleepGlucose IntoleranceFeeding Patterns
Massachusetts General Hospital30 enrolled1 locationNCT04737200
Recruiting
Phase 2

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Cystic FibrosisDiabetesPancreatic Insufficiency+1 more
University of Pennsylvania30 enrolled2 locationsNCT04731272
Recruiting
Not Applicable

Night Owl Metabolism

OverweightPrediabetesImpaired Glucose Tolerance
Johns Hopkins University70 enrolled1 locationNCT06507722
Recruiting
Phase 1Phase 2

Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

Kidney TransplantToleranceRenal Transplant Rejection
Jeffrey Veale, MD15 enrolled1 locationNCT03707262
Recruiting
Not Applicable

Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers

Intolerance to "Conventional" Bread
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement40 enrolled2 locationsNCT07568223
Recruiting
Not Applicable

Hypercapnia and Orthostatic Tolerance in Postural Orthostatic Tachycardia Syndrome

Orthostatic intolerancePostural Tachycardia Syndrome
University of Calgary26 enrolled1 locationNCT04271878
Recruiting

Kidney Graft Tolerance KTOL

Kidney Transplant Tolerance
Nantes University Hospital15 enrolled1 locationNCT06271343
Recruiting
Not Applicable

Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading

Orthostatic intolerance
Tracy Baynard64 enrolled1 locationNCT06939153
Recruiting
Not Applicable

Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.

Traumatic Brain InjuryNeurocritical CareEnteral Feeding Intolerance
Tang-Du Hospital100 enrolled1 locationNCT07092423
Recruiting
Not Applicable

Paediatric Syncope in the Emergency Department

Postural Orthostatic tachycardia SyndromeOrthostatic intoleranceSyncope, Vasovagal
Dr. Victoria Claydon300 enrolled1 locationNCT05555771
Recruiting
Not Applicable

Postural Sway and Counterpressure Maneuvers for Pediatric Syncope

Postural Orthostatic tachycardia SyndromeOrthostatic intoleranceSyncope, Vasovagal
Simon Fraser University30 enrolled1 locationNCT05633693
Recruiting
Not Applicable

FMT for Lung and Associated-organ Rescue Efficacy in ARDS Patients

Lung InfectionMicrobial ColonizationFood Intolerance Syndromes
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology150 enrolled1 locationNCT06970262
Recruiting
Not Applicable

Oral Nutritional Supplement in Adults With or at Risk of Malnutrition

Gastrointestinal Tolerance
Abbott Nutrition25 enrolled3 locationsNCT07426406