Phase 4 Total Knee Arthroplasty Clinical Trials

12 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 112 of 12 trials

Recruiting
Phase 4

Medrol Dosepak for Outpatient Total Knee Arthroplasty

Total Knee Arthroplasty
Rush University Medical Center420 enrolled1 locationNCT05097976
Recruiting
Phase 4

Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients

Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4

A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty

Total Knee Arthroplasty
University of California, San Diego30 enrolled1 locationNCT07282782
Recruiting
Phase 4

Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty

Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Not Yet Recruiting
Phase 4

Extended Postoperative Oral Tranexamic Acid In Total Hip and Knee Arthroplasty: A Randomised Controlled Study

OsteoarthritisTotal Hip ArthroplastyTotal Knee Arthroplasty
North Sydney Orthopaedic Research Group200 enrolled1 locationACTRN12625000926437
Recruiting
Phase 4

Kinematic and Mechanical Alignment Randomized Trial

OsteoarthritisTotal Knee Arthroplasty
McMaster University260 enrolled1 locationNCT06787417
Completed
Phase 4

Investigating the effect of tranexamic acid on recovery time in patients undergoing total knee replacements

Peri-operative bleeding with Total Knee ArthroplastyTotal Knee Arthroplasty
Wesley Medical Research80 enrolled2 locationsACTRN12621001327875
Recruiting
Phase 4

Optimising pain relief after knee joint replacement surgery at Counties Manukau Health; We compare two methods of local anaesthesia (numbing medicine) administration to reduce pain after knee replacement surgery.

Pain relief after Total Knee Arthroplasty
Counties Manukau Health, Middlemore Hospital Research Office72 enrolled1 locationACTRN12619000221156
Terminated
Phase 4

A clinical trial to determine if aspirin is as effective and safe as low molecular weight heparin in preventing lung and leg clots after total hip or knee replacement surgery

Venous Thromboembolic Events (VTE) after Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
University of New South Wales15,562 enrolled1 locationACTRN12618001879257
Recruiting
Phase 4

Postoperative analgesia for elective total knee arthroplasty

Postoperative analgesia for elective total knee arthroplasty
Hospital Complex of Navarra500 enrolled1 locationACTRN12616000912482
Completed
Phase 4

Comparision of Intraoperative Epidural Analgesia and Intraoperative Periarticular Injection on Pain Control After Total Knee Arthroplasty

postoperative analgesia after total knee arthroplasty
Namik Sahin128 enrolled1 locationACTRN12616000226404
Recruiting
Phase 4

Optimizing post operative outcomes in Total Knee Arthroplasty (TKR) through improved pain and fatigue management: a randomized placebo controlled trial.

Post Operative Management of Total Knee ArthroplastyKnee Osteoarthritis
ORIQL104 enrolled1 locationACTRN12615000413527