Phase 2 Transplantation Clinical Trials

71 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 71 trials

Recruiting
Phase 1Phase 2

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 2

Precision Alemtuzumab Dosing for Allogeneic Hematopoietic Cell Transplantation

Allogeneic Hematopoietic Cell Transplantation
Children's Hospital Medical Center, Cincinnati60 enrolled1 locationNCT05501756
Recruiting
Phase 2

Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant Recipients

HypophosphatemiaKidney Transplantation
Stanford University90 enrolled1 locationNCT06824454
Recruiting
Phase 1Phase 2

Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)

Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 1Phase 2

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

Sickle Cell DiseaseGraft FailureHematopoetic Stem Cell Transplant+2 more
Arkansas Children's Hospital Research Institute24 enrolled4 locationsNCT07252050
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763
Recruiting
Phase 2

LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.

Bronchiolitis Obliterans SyndromeLung transplantationChronic lung allograft dysfunction
Steven Hays, MD30 enrolled1 locationNCT06018766
Recruiting
Phase 2Phase 3

VABu Conditioning in Elderly AML HSCT

Acute Myeloid Leukemia (AML)Allogeneic Hematopoietic Stem Cell Transplantation Recipient
The First Affiliated Hospital of Soochow University20 enrolled1 locationNCT07583888
Recruiting
Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Acute Lymphoblastic LeukemiaAcute LeukemiaMyeloproliferative Neoplasm+14 more
Fred Hutchinson Cancer Center68 enrolled10 locationsNCT03779854
Recruiting
Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Hematopoietic Stem Cell TransplantationImmunodeficiency
National Cancer Institute (NCI)54 enrolled1 locationNCT05027945
Recruiting
Phase 2

Moxibustion for Steroid-Refractory Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Acute Graft Versus Host DiseaseGraft-Versus-Host DiseaseALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology42 enrolled1 locationNCT07572669
Recruiting
Phase 2

Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors

Graft-Versus-Host-Disease (GVHD)Bone Marrow Transplantation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine82 enrolled1 locationNCT07570745
Recruiting
Phase 2

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Acute Kidney InjuryHeart Transplantation
Fernando Bacal74 enrolled1 locationNCT05909150
Recruiting
Phase 2

Phase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation

Kidney TransplantationAMRAntibody-mediated Rejection+1 more
Alexion Pharmaceuticals, Inc.45 enrolled55 locationsNCT06744647
Recruiting
Phase 2

Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen

Peripheral Blood Stem Cell Transplantation
Chinese PLA General Hospital50 enrolled1 locationNCT05088226
Recruiting
Phase 2

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

Kidney Transplantation
Singulera Therapeutics Inc.34 enrolled7 locationsNCT06552169
Recruiting
Phase 2

Imlifidase Prior to Kidney Transplant in Highly Sensitised Children

Kidney Transplantation in Highly Sensitized Patients
Hansa Biopharma AB10 enrolled5 locationsNCT05753930
Recruiting
Phase 2

Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant

allogeneic stem cell transplantation
Children's Hospital Medical Center, Cincinnati419 enrolled3 locationsNCT05579639
Recruiting
Phase 2

Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaTransplantation, Stem Cell+1 more
The First Affiliated Hospital of Soochow University48 enrolled1 locationNCT06816134
Recruiting
Phase 2

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

InfluenzaTransplantation InfectionImmunization; Infection
National Institute of Allergy and Infectious Diseases (NIAID)312 enrolled8 locationsNCT05947071