Phase 2 Transplantation Clinical Trials

56 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 56 trials

Recruiting
Phase 1Phase 2

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Hematopoietic Stem Cell TransplantationImmunodeficiency
National Cancer Institute (NCI)54 enrolled1 locationNCT05027945
Recruiting
Phase 2

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

Kidney Transplantation
Singulera Therapeutics Inc.34 enrolled7 locationsNCT06552169
Recruiting
Phase 2

Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen

Peripheral Blood Stem Cell Transplantation
Chinese PLA General Hospital50 enrolled1 locationNCT05088226
Recruiting
Phase 2

Imlifidase Prior to Kidney Transplant in Highly Sensitised Children

Kidney Transplantation in Highly Sensitized Patients
Hansa Biopharma AB10 enrolled5 locationsNCT05753930
Recruiting
Phase 2

Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaTransplantation, Stem Cell+1 more
The First Affiliated Hospital of Soochow University48 enrolled1 locationNCT06816134
Recruiting
Phase 2

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

InfluenzaTransplantation InfectionImmunization; Infection
National Institute of Allergy and Infectious Diseases (NIAID)312 enrolled8 locationsNCT05947071
Recruiting
Phase 2

Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients

Oral MucositisHematopoietic Stem Cell TransplantationStomatitis+1 more
The First Affiliated Hospital of Soochow University22 enrolled1 locationNCT07400328
Recruiting
Phase 2Phase 3

CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients

Kidney Pancreas Transplantation
University of Wisconsin, Madison20 enrolled1 locationNCT03769298
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled2 locationsNCT06878560
Recruiting
Phase 1Phase 2

Immune Tolerance Induction After Liver Transplantation

Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 2

Orphan Indications for CD19 Redirected Autologous T Cells

Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALLInfants With Very High Risk KMT2A B-ALLPatients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation
Stephan Grupp MD PhD133 enrolled1 locationNCT04276870
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 2

Study of Organ Perfusion in Heart Transplantation in Children

Heart Transplantation
Dr. F. Köhler Chemie GmbH15 enrolled3 locationsNCT06032195
Recruiting
Phase 2

G-CSF Combined With IL-11 on Hematopoietic Reconstitution After Autologous Hematopoietic Stem Cell Transplantation

Hematopoetic Stem Cell TransplantationHemato-oncologic PatientsMobilization of Hematopoietic Stem Cells (HSC) to Peripheral Blood (PB)
Fudan University224 enrolled3 locationsNCT07362810
Recruiting
Phase 1Phase 2

The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients

Kidney TransplantationDelayed Graft Function
First Affiliated Hospital of Chongqing Medical University47 enrolled2 locationsNCT07275632
Recruiting
Phase 2

Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML

AML (Acute Myeloid Leukemia)Allogeneic Hematopoietic Cell Transplantation (HCT)
Institute of Hematology & Blood Diseases Hospital, China134 enrolled5 locationsNCT07304232
Recruiting
Phase 2

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

InfluenzaTransplantation InfectionImmunization; Infection
Vanderbilt University Medical Center270 enrolled1 locationNCT05215327
Recruiting
Phase 2

Belatacept in De Novo Heart Transplantation

Heart Transplantation
NYU Langone Health12 enrolled2 locationsNCT04477629
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD

Kidney TransplantationXenotransplantationESRD (End-Stage Renal Disease)
United Therapeutics50 enrolled1 locationNCT07224763