Phase 2 Treatment Resistant Depression Clinical Trials
16 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–16 of 16 trials
Recruiting
Phase 2
Mindfulness Engaged Neurostimulation for Depression (MEND II)
DepressionDepressive DisorderDepressive Symptoms+2 more
University of California, San Diego120 enrolled1 locationNCT07512284
Recruiting
Phase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
Treatment Resistant Depression
atai Therapeutics, Inc.142 enrolled42 locationsNCT06524830
Recruiting
Phase 2
Antidepressant Effects of Nitrous Oxide
Major Depressive DisorderTreatment Resistant Depression
University of Chicago172 enrolled2 locationsNCT05357040
Recruiting
Phase 2
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
SuicideMajor Depressive DisorderTreatment Resistant Depression
University Health Network, Toronto110 enrolled1 locationNCT06480500
Recruiting
Phase 2
An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression
Treatment Resistant Depression
Beckley Psytech Limited64 enrolled3 locationsNCT05660642
Recruiting
Phase 2
Psilocybin rTMS for Treatment Resistant Depression
DepressionMajor Depressive DisorderTreatment Resistant Depression+2 more
University of Texas at Austin100 enrolled1 locationNCT06132178
Recruiting
Phase 2
Psilocybin Microdosing With Psychotherapy for Treatment-Resistant Depression
Treatment Resistant Depression
Beersheva Mental Health Center20 enrolled1 locationNCT07183748
Recruiting
Phase 2
Intravenous Ketamine for Treatment-Resistant Depression
Treatment Resistant Depression (TRD)Depressive Disorder, Treatment-Resistant
Mayo Clinic30 enrolled1 locationNCT06668571
Recruiting
Phase 2
Mindfulness Engaged Neurostimulation for Depression
DepressionDepressive DisorderMajor Depressive Disorder+1 more
University of California, San Diego70 enrolled1 locationNCT06399406
Recruiting
Phase 2
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
Treatment Resistant Depression
Centre for Addiction and Mental Health12 enrolled1 locationNCT06512220
Recruiting
Phase 2
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Chronic PainTreatment Resistant Depression
Centre for Addiction and Mental Health16 enrolled1 locationNCT06518720
Not Yet Recruiting
Phase 2
Psilocybin Medicine Open-Label Study (PMOS): a determination of the safety and efficacy of psilocybin-assisted psychotherapy for patients with Treatment Resistant Major Depressive Disorder (TRD) within an Australian clinical context.
Treatment Resistant Depression
GoodMind Therapeutics50 enrolled1 locationACTRN12624001343594
Recruiting
Phase 2
Psilocybin for Hospitalized Patients with Treatment-resistant Depression
Treatment Resistant Depression
University Hospital, Ghent100 enrolled1 locationNCT06378229
Recruiting
Phase 2
Evaluating the management of treatment resistant depression with psychedelic (psilocybin) assisted psychotherapy (EMPACT)
Treatment Resistant Depression
The Australian National University140 enrolled1 locationACTRN12623001004651
Completed
Phase 2
A study of psilocybin-assisted psychotherapy for treatment-resistant depression (TRD)
Treatment Resistant Depression (TRD)
Swinburne University of Technology15 enrolled1 locationACTRN12621001097831
Completed
Phase 2
Probiotics and Orotic Acid and antidepressant medication for treatment resistant depression; a pilot study
treatment resistant depression with high relapse risk
university of Queensland30 enrolled1 locationACTRN12614000544673