Phase 4 Treatment Clinical Trials

42 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 42 trials

Recruiting
Phase 4

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

Acute Treatment of Migraine
Pfizer400 enrolled3 locationsNCT07609914
Recruiting
Phase 4

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression

Treatment Resistant Depression
The George Institute162 enrolled7 locationsNCT06278779
Recruiting
Phase 4

Establishing Mobile Transcranial Magnetic Stimulation

Treatment Resistant Major Depression
Medical University of South Carolina30 enrolled1 locationNCT06748209
Recruiting
Phase 4

Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression

Treatment Resistant Depression (TRD)
Aalborg University Hospital80 enrolled1 locationNCT07080723
Recruiting
Phase 4

Effect Clomiphene vs Clomiphene Along With Pioglitazone on Ovarian Stimulation Rate

Infertility TreatmentPregnancy Rates
PAEC General Hospital, Islamabad62 enrolled1 locationNCT07462065
Recruiting
Phase 4

Esketamine With or Without Integration Therapy for Treatment-Resistant Depression

Treatment Resistant Depression (TRD)
University of Puerto Rico20 enrolled2 locationsNCT07369102
Recruiting
Phase 4

Ketorolac Use and Fresh Embryo Transfer Outcomes

Infertility (IVF Patients)Fresh Embryo TransferInfertility Treatment+2 more
Jessica D. Kresowik200 enrolled1 locationNCT07185724
Recruiting
Phase 4

Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.

Postoperative PainPostoperative Adjuvant TreatmentPostoperative Pain Management+4 more
Instituto Mexicano del Seguro Social104 enrolled2 locationsNCT07073846
Recruiting
Phase 4

A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia

Clinical Characteristics and Treatment Outcomes of Malignant Tumor CachexiaMulticenter Observational Study
Changchun GeneScience Pharmaceutical Co., Ltd.495 enrolled1 locationNCT07243379
Recruiting
Phase 4

The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

Schizophrenia and Related DisordersEarly Treatment-Resistance
Dr. Inge Winter418 enrolled13 locationsNCT05958875
Recruiting
Phase 4

Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting

DexmedetomidineCoronary Artery Bypass GraftingPregabalin+1 more
Tanta University70 enrolled1 locationNCT05640453
Recruiting
Phase 4

Safety, Tolerability and Effectiveness of DTG/3TC vs BIC/TAF/FTC in PWH Without Antiretroviral Experience

Metabolic SyndromeHIV InfectionAntiretroviral Treatment
Instituto Mexicano del Seguro Social124 enrolled1 locationNCT07031063
Recruiting
Phase 4

ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression

Treatment Resistant DepressionKetamine
University of Saskatchewan62 enrolled1 locationNCT03272698
Recruiting
Phase 4

Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy

Acute appendicitisMultimodal AnalgesiaOpioid Consumption+1 more
Medical University of Warsaw188 enrolled1 locationNCT06563349
Recruiting
Phase 4

Multi-center Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot Ulcer

Diabetic Foot Ulcer Treatment
Peking University Third Hospital100 enrolled1 locationNCT06197412
Recruiting
Phase 4

Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery

Growth Hormone Treatment
Shanghai Zhongshan Hospital40 enrolled1 locationNCT06448195
Recruiting
Phase 4

Two Regimens of IVIG in the Treatment of Newly Diagnosed ITP in Children

Newly Diagnosed Immune Thrombocytopenia in Children, First Line Treatment
Fujian Medical University Union Hospital580 enrolled1 locationNCT05520892
Recruiting
Phase 4

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

TreatmentAdjuvantTuberculosis
Beijing Chest Hospital292 enrolled1 locationNCT06403943
Recruiting
Phase 4

Effectiveness of Psychedelic Therapy for Treatment Resistant Depression (TRD)

Treatment Resistant Depression (TRD)
Dr and A/ Professor Ranil Gunewardene30 enrolled1 locationACTRN12624000040561