Phase 1 Treatment Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
Venetoclax Basket Trial for High Risk Hematologic Malignancies
Acute Lymphoblastic Leukemia, in RelapseAcute Leukemia of Ambiguous LineageAcute Lymphoblastic Leukemia With Failed Remission+8 more
Andrew E. Place, MD30 enrolled5 locationsNCT05292664
Recruiting
Phase 1Phase 2
Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML
TreatmentAMLIDH1 Mutation
Institute of Hematology & Blood Diseases Hospital, China29 enrolled1 locationNCT06611839
Recruiting
Phase 1
Psilocybin for Treatment-Resistant Depression in Autism
Autism Spectrum DisorderTreatment Resistant Depression
Centre for Addiction and Mental Health20 enrolled1 locationNCT06731621
Recruiting
Phase 1
Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
HealthyMajor Depressive DisorderTreatment Resistant Depression
Baylor College of Medicine100 enrolled2 locationsNCT06480201
Recruiting
Phase 1
DBS for Depression
Treatment Resistant Depression
Northwell Health20 enrolled1 locationNCT06096207
Recruiting
Phase 1Phase 2
Personalized Ultrasonic Brain Stimulation for Depression (R61)
Depression - Major Depressive DisorderMajor Depressive EpisodeTreatment-Resistant Major Depressive Disorder
Brian Mickey30 enrolled1 locationNCT06902298
Recruiting
Phase 1
VSV-02 Compassionate Use in Advanced Solid Tumors
Breast CancerLung CancerMelanoma+3 more
The First Affiliated Hospital of Xinxiang Medical College6 enrolled1 locationNCT07260591
Recruiting
Phase 1
Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression
Treatment-resistant Bipolar Depression
The University of Texas Health Science Center, Houston30 enrolled1 locationNCT03522545
Recruiting
Phase 1
Hepatic Artery Transfusion of NKG2D CAR-NK Cells Followed by Intravenous Infusion of NKG2D CAR-T Cells to Treat Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments: a Phase I Exploratory Clinical Trial
Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments
Zhejiang University12 enrolled1 locationNCT07021534
Recruiting
Phase 1Phase 2
A Study of AK104 Plus Axitinib in Advanced/Metastatic Special Pathological Subtypes of Renal Cell Carcinoma
Renal Cell CarcinomaFirst-line TreatmentSarcomatoid Renal Cell Carcinoma+1 more
Hao Zeng33 enrolled1 locationNCT05808608
Recruiting
Phase 1Phase 2
Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy
Neoadjuvant TreatmentRectal CancerRadiotherapy+1 more
Shanghai Minimally Invasive Surgery Center20 enrolled1 locationNCT05111860