Phase 1 Tuberculosis Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1
Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis
TuberculosisRifampicin Resistant Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)72 enrolled6 locationsNCT05586230
Recruiting
Phase 1
Precision Rifampin Trial for Personalized Dosing
Tuberculosis
University of Virginia200 enrolled1 locationNCT06318416
Recruiting
Phase 1
A Study to Evaluate the Safety and Immunogenicity of Ad5-105K in Adults Aged 18 to 49 Years
Tuberculosis
CanSino Biologics Inc.36 enrolled1 locationNCT06732583
Recruiting
Phase 1
Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin
Pediatric HIV InfectionTuberculosis Infection
Brigham and Women's Hospital20 enrolled1 locationNCT05069688
Recruiting
Phase 1
ID93+GLA-SE Vaccine Against Tuberculosis in Older Adults Aged 55-74
Tuberculosis, Pulmonary
Quratis Inc.144 enrolled4 locationsNCT06714513
Recruiting
Phase 1
Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention
Pediatric HIV InfectionLatent Tuberculosis
Brigham and Women's Hospital25 enrolled1 locationNCT06281834
Recruiting
Phase 1
Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy
Tuberculosis Infection
University of Zurich16 enrolled1 locationNCT05443178
Recruiting
Phase 1
Inhaled rifampicin study in healthy individuals
Tuberculosis
University of Otago50 enrolled1 locationACTRN12617001643369