Phase 2 Tuberculosis Clinical Trials
24 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 24 trials
Recruiting
Phase 2
Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis
Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute150 enrolled13 locationsNCT07525427
Recruiting
Phase 2Phase 3
Shorter and Safer Treatment Regimens for Latent TB
Tuberculosis Infection, Latent
McGill University Health Centre/Research Institute of the McGill University Health Centre1,800 enrolled13 locationsNCT06498414
Recruiting
Phase 2
Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis
Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute165 enrolled4 locationsNCT07517445
Recruiting
Phase 2
Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis
Pulmonary Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)315 enrolled29 locationsNCT06192160
Recruiting
Phase 2
Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents With Pulmonary MDR-TB
Tuberculosis, Multidrug-Resistant
Janssen Research & Development, LLC60 enrolled11 locationsNCT02354014
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living in a TB Endemic Region.
Tuberculosis (TB)
International AIDS Vaccine Initiative5,500 enrolled16 locationsNCT06272812
Recruiting
Phase 2
Evaluating the Safety and Immunogenicity of MTBVAC
TuberculosisHIV I Infection
HIV Vaccine Trials Network276 enrolled16 locationsNCT05947890
Recruiting
Phase 2
A Phase 2b Clinical Study of JDB0131 Benzenesulfonate Tablets
TuberculosisMultidrug Resistant Pulmonary Tuberculosis
WestVac Biopharma Co., Ltd.60 enrolled7 locationsNCT07170800
Recruiting
Phase 2
ATORvastatin in Pulmonary TUBerculosis: a POPulation PharmacoKinetics -PharmacoDynamics Sub-study (ATORTUB popPK-PD)
Pulmonary Tuberculosis (TB)
Obafemi Awolowo University Teaching Hospital80 enrolled3 locationsNCT07303699
Recruiting
Phase 2Phase 3
Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR
University of California, San Francisco400 enrolled6 locationsNCT06441006
Recruiting
Phase 2
PanACEA - STEP2C -01
Pulmonary TuberculosisOther Specified Pulmonary Tuberculosis
Michael Hoelscher390 enrolled10 locationsNCT05807399
Recruiting
Phase 2
Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
Pulmonary Tuberculosis
University College, London2,500 enrolled11 locationsNCT06114628
Recruiting
Phase 2
ATORvastatin in Pulmonary TUBerculosis
TuberculosisPulmonary TuberculosisKoch's Disease
Obafemi Awolowo University Teaching Hospital440 enrolled8 locationsNCT06199921
Recruiting
Phase 2
Adjunctive Doxycycline for Central Nervous System Tuberculosis
Tuberculosis, MeningealTuberculosis; Meningitis (Etiology)Tuberculosis, Central Nervous System+1 more
National University Hospital, Singapore200 enrolled5 locationsNCT06446245
Recruiting
Phase 2
Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine MTBVAC in Healthy Indian Adults and Adolescents (BBV169/2024)
Tuberculosis (TB)
Bharat Biotech International Limited164 enrolled2 locationsNCT06997367
Recruiting
Phase 2
Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB
Tuberculosis, Multidrug-Resistant
Boston University220 enrolled2 locationsNCT03828201
Recruiting
Phase 2
Characterization of Tuberculosis Associated Lung Fibrosis and Respiratory Impairment, and Prevention Using Doxycycline
Tuberculosis, Pulmonary
Makerere University200 enrolled2 locationsNCT06477185
Recruiting
Phase 2
A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide
Tuberculosis
TASK Applied Science60 enrolled1 locationNCT06748937
Recruiting
Phase 2
Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB)
Tuberculosis
Assistance Publique - Hôpitaux de Paris60 enrolled1 locationNCT05534750
Recruiting
Phase 2Phase 3
DeMONSTRATE-TB Study in Ethiopia
Reducing Tuberculosis Incidence
Management Sciences for Health131,438 enrolled2 locationsNCT06719193