Early Phase 1 Tumors Clinical Trials
34 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 34 trials
Recruiting
Early Phase 1
AMT-676 in Patients With Advanced Solid Tumors
Advanced Solid Tumors
Multitude Therapeutics Inc.24 enrolled13 locationsNCT06400485
Recruiting
Early Phase 1
A IIT Study of 177Lu-DOTA-SNA040
Advanced Solid Tumors (Such as Gastric Cancer)Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction)Advanced Solid Tumors (Such as Pancreatic Cancer)+1 more
SmartNuclide Biopharma12 enrolled1 locationNCT07595237
Recruiting
Early Phase 1
SPH5030 Tablets in Subjects With Advanced Her2-positive Solid Tumors
HER2-Positive Advanced Solid Tumors
Shanghai Pharmaceuticals Holding Co., Ltd150 enrolled17 locationsNCT05245058
Recruiting
Early Phase 1
NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors
Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
PainBrain InjuryBrain Tumors+3 more
University of Virginia40 enrolled1 locationNCT06810336
Recruiting
Early Phase 1
Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors
Solid Tumors
Nanolattix Biotechnology Co., Ltd.10 enrolled1 locationNCT07505069
Recruiting
Early Phase 1
Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1
A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors
NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813
Recruiting
Early Phase 1
A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.
Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1
HEAT Trial (HER2 Antibody Therapy With Lutetium-177)
Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1
A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]
Primary Malignant Peripheral Nerve Sheath Tumors
University of Minnesota8 enrolled1 locationNCT06693284
Recruiting
Early Phase 1
A Clinical Study of GK02 in Malignant Ascites
Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1
Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences36 enrolled1 locationNCT07349160
Recruiting
Early Phase 1
Clinical Application of 68Ga-FL-031 PET in the Diagnosis and Staging of Malignant Tumors
PETSSTR2Malignant Tumors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology10 enrolled1 locationNCT07301801
Recruiting
Early Phase 1
A Study of GC101 TIL in Advanced Solid Tumors (TR)
Advanced Solid Tumors
Shanghai Juncell Therapeutics20 enrolled1 locationNCT04967833
Recruiting
Early Phase 1
A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital)
Treatment Side EffectsEffects of ImmunotherapyAdvanced Gynecologic Tumors+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098171
Recruiting
Early Phase 1
Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Anhui Provincial Hospital36 enrolled1 locationNCT07106814
Recruiting
Early Phase 1
HF50 in HER-2 Positive and Low-expression Advanced Solid Tumors
Advanced Solid Tumors
HighField Biopharmaceuticals Corporation10 enrolled1 locationNCT06822998
Recruiting
Early Phase 1
Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors
Pancreatic NeoplasmsOther Solid Tumors
Ruijin Hospital56 enrolled1 locationNCT06577532
Recruiting
Early Phase 1
Personalized KSX01-TCRT in Patients With Advanced Solid Tumors
Refractory Solid TumorsRelapsed Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences12 enrolled1 locationNCT06150365