Venous Insufficiency Clinical Trials

3 recruitingLast updated: May 6, 2026

There are 14 actively recruiting venous insufficiency clinical trials across 6 countries. Studies span Not Applicable, Phase 3. Top locations include Chengdu, Sichuan, China, Fort Worth, Texas, United States, Jacksonville, Florida, United States. Updated daily from ClinicalTrials.gov.


Venous Insufficiency Trials at a Glance

14 actively recruiting trials for venous insufficiency are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Chengdu, Fort Worth, and Jacksonville. Lead sponsors running venous insufficiency studies include Chengdu University of Traditional Chinese Medicine, TR Therapeutics, and GCS Ramsay Santé pour l'Enseignement et la Recherche.

Browse venous insufficiency trials by phase

Treatments under study

About Venous Insufficiency Clinical Trials

Looking for clinical trials for Venous Insufficiency? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Venous Insufficiency trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Venous Insufficiency clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Not Applicable

Therapeutic Efficacy of the Phlebology-oriented Thermal Cure at the Saint-Eloy Thermal Center in the Treatment of Symptoms of Severe Chronic Venous Insufficiency

Venous Insufficiency of Leg
Société d'Exploitation des Thermes d'Amnéville84 enrolled1 locationNCT07362719
Recruiting
Not Applicable

The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression

Chronic venous insufficiencyVaricose Veins
Pirogov Russian National Research Medical University400 enrolled1 locationNCT07449728
Recruiting
Phase 3

Tissue Repair Gel in Venous Leg Ulcers (US)

WoundsWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled33 locationsNCT06707090
Recruiting
Not Applicable

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

Venous InsufficiencyVenous Leg UlcerNon-infected Venous Leg Ulcer+2 more
BioStem Technologies60 enrolled23 locationsNCT06811909
Recruiting
Not Applicable

Minimally Invasive Superficial Venous Insufficiency Surgery and Digital Sedation

Superficial Venous Insufficiency
GCS Ramsay Santé pour l'Enseignement et la Recherche400 enrolled2 locationsNCT06228365
Recruiting

Risks and Benefits of Radiofrequency Ablation for Chronic Venous Insufficiency (CEAP C3-C6) in Patients Aged 80 and Over

Radiofrequency AblationCohort StudyChronic Venous Insufficiency, CVI+1 more
Chengdu University of Traditional Chinese Medicine50 enrolled1 locationNCT07233616
Recruiting

Reducing Skin Tone Inequities in Chronic Venous Insufficiency

Venous Leg Ulcer (VLU)Chronic Venous Insufficiency, CVIChronic Venous Insufficiency C2 or Higher+1 more
King's College London51 enrolled2 locationsNCT06798766
Recruiting
Phase 3

Tissue Repair Gel in Venous Leg Ulcers in AU/US

WoundWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled12 locationsNCT06707103
Recruiting
Not Applicable

Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous Varicose Veins

Vascular Disease,PeripheralVenous Insufficiency of LegVaricose Veins of Lower Limb
Chengdu University of Traditional Chinese Medicine150 enrolled1 locationNCT06711120
Recruiting

Observation of Pain During the Treatment of Great Saphenous Vein Using Microwave Ablation, and Analysis of Related Factors

Vascular Disease,PeripheralVenous Insufficiency of LegVaricose Veins of Lower Limb
Chengdu University of Traditional Chinese Medicine155 enrolled1 locationNCT06693245
Recruiting
Not Applicable

The ROle of Compression StocKings in Heart Failure Patients

Heart Failure, CongestiveVenous InsufficiencyVenous Ulcers+1 more
University of Maryland, Baltimore50 enrolled1 locationNCT06350695
Recruiting
Not Applicable

Comparative Clinical Efficacy Between Multi-layer Bandage Pressure Therapy and Gradient Pressure Elastic Stocking Treatment After Endovenous Radiofrequency Ablation

Venous Insufficiency of LegVaricose Veins of Lower LimbVascular Diseases, Peripheral
Chengdu University of Traditional Chinese Medicine210 enrolled1 locationNCT06366763
Recruiting

Prospective Cohort Study for Varicose Veins Incidence and Natural Course

Venous InsufficiencyThromboses, VenousVaricose Veins of Lower Limb
Russian Phlebological Association100 enrolled1 locationNCT04546750
Recruiting

Non-contact monitoring of blood flow to the legs of people with diabetes (HeMo)

Chronic venous insufficiencyDiabetes
South Western Sydney Local Health District100 enrolled1 locationACTRN12619001173189