Phase 2 Volunteer Clinical Trials

32 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 32 trials

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled87 locationsNCT06649110
Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1Phase 2

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

Healthy VolunteersAnemia, Sickle Cell
Bristol-Myers Squibb224 enrolled33 locationsNCT06481306
Recruiting
Phase 2

Role of a Mitochondrial Receptor in Blood Sugar Regulation

Heathly Volunteers
Imperial College London50 enrolled1 locationNCT07682233
Recruiting
Phase 1Phase 2

Classroom Break, Cognition, and Fitness in Elementary School Children

Healthy Volunteers
Purdue University352 enrolled1 locationNCT06258941
Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.

Healthy VolunteersSclerodermaSystemic Sclerosis (SSc)+1 more
Prolium Bioscience, Inc44 enrolled3 locationsNCT07641634
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled22 locationsNCT06845202
Recruiting
Phase 1Phase 2

Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions

Healthy VolunteerVancomycinHypersensitivity Reactions
Johns Hopkins University25 enrolled1 locationNCT07605806
Recruiting
Phase 1Phase 2

Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia

Androgenetic alopecia (AGA)Healthy Volunteers - Male and Female
Absci Pty Ltd.227 enrolled4 locationsNCT07317544
Recruiting
Phase 1Phase 2

A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease

Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679
Recruiting
Phase 1Phase 2

Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause

Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1Phase 2

To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI)

Healthy Volunteers
Juvena Therapeutics36 enrolled2 locationsNCT07397468
Recruiting
Phase 1Phase 2

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Healthy VolunteersMetabolic dysfunction–associated steatotic liver disease (MASLD)
Regeneron Pharmaceuticals172 enrolled6 locationsNCT05648214
Recruiting
Phase 2

Ultralow Dose PET Imaging of SSTR2 Radiotracer Uptake

Healthy VolunteersHealthy (Controls)Neuroendocrine (NE) Tumors
Akiva Mintz200 enrolled1 locationNCT07284589
Recruiting
Phase 2

Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol

DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 1Phase 2

Dose Escalation Trial of CD40.Pan.CoV Vaccine, Adjuvanted or Not, as a Booster in Adult Healthy Volunteers

Healthy Volunteers
ANRS, Emerging Infectious Diseases48 enrolled7 locationsNCT07113106
Recruiting
Phase 2

Ultralow Dose PET Imaging for 18F-NaF Uptake

Healthy VolunteerArthritisBone and Joint Infection+2 more
Akiva Mintz200 enrolled2 locationsNCT07284563