Phase 1 Volunteer Clinical Trials
254 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 254 trials
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled87 locationsNCT06649110
Recruiting
Phase 1
A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 Diabetes
Healthy VolunteerType 2 Diabetes
Novo Nordisk A/S60 enrolled1 locationNCT07270731
Recruiting
Phase 1
Study Evaluating Safety & Tolerability of Migaldendranib in Healthy Volunteers
Healthy Volunteers
Ashvattha Therapeutics, Inc.36 enrolled1 locationNCT07370155
Recruiting
Phase 1
Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection
Healthy VolunteersDengueHuman Challenge Trial
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled1 locationNCT07706686
Recruiting
Phase 1
A Study of B-3E07 and Forsteo® in Healthy Adult Female Participants
Healthy Volunteers
Syneos Health48 enrolled1 locationNCT07497503
Recruiting
Phase 1
Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake
Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301
Recruiting
Phase 1
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
Healthy Volunteer Study
Atea Pharmaceuticals, Inc.32 enrolled3 locationsNCT07314346
Recruiting
Phase 1
Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
Non-small Cell Lung Cancer (NSCLC)Ovarian CancerCervical Cancer+4 more
Radiopharm Theranostics, Ltd9 enrolled2 locationsNCT05799274
Recruiting
Phase 1
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of TESP-0401 in Healthy Participants
Healthy Volunteers
Tes Pharma S.r.l.68 enrolled1 locationNCT07658638
Recruiting
Phase 1
Dimotec (Diosmin) 1000 mg Film Coated Tablet Fed Study
Healthy Volunteers
Keri Pharma Hungary Kft72 enrolled1 locationNCT07674446
Recruiting
Phase 1
A Study to Evaluate the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379
Healthy Volunteers
Mirum Pharmaceuticals, Inc.8 enrolled1 locationNCT07712718
Recruiting
Phase 1
A Study of the Pharmacokinetics and Safety of Single-dose Inhaled RJ026 in Healthy Volunteers and Patients With Interstitial Lung Disease
Healthy VolunteersInterstitial Lung Disease (ILD)
Ruijin Hospital84 enrolled1 locationNCT06992661
Recruiting
Phase 1
A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)
Rheumatoid ArthritisHealthy VolunteersSystemic Lupus Erythematosus
Capstan Therapeutics64 enrolled3 locationsNCT06917742
Recruiting
Phase 1
A Study to Evaluate ALN-4285 in Adult Healthy Volunteers
Healthy Volunteers
Alnylam Pharmaceuticals76 enrolled1 locationNCT07295717
Recruiting
Phase 1
Study of Food Effects of VV913 Capsules in Chinese Healthy Volunteers
Healthy Volunteers
Vigonvita Life Sciences12 enrolled1 locationNCT07565792
Recruiting
Phase 1
A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease
stable coronary artery diseaseHealthy Volunteers
Hoffmann-La Roche196 enrolled1 locationNCT07495813
Recruiting
Phase 1
A Trial to Assess TEV-56286 at Different Doses in Healthy Participants
Healthy Volunteers
Teva Branded Pharmaceutical Products R&D LLC60 enrolled1 locationNCT07674940
Recruiting
Phase 1
A Positron Emission Tomography Study to Assess the Occupancy of M4 Muscarinic Acetylcholine Receptors by BMS-986521 in Healthy Adult Participants
Healthy Volunteers
Bristol-Myers Squibb12 enrolled1 locationNCT07655518
Recruiting
Phase 1
A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants
Healthy Volunteers
BeOne Medicines30 enrolled1 locationNCT07590102
Recruiting
Phase 1
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
Healthy VolunteerSafetyPharmacokinetics+2 more
Basilea Pharmaceutica96 enrolled1 locationNCT06733675