Phase 1 Volunteer Clinical Trials
211 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 211 trials
Recruiting
Phase 1Phase 2
Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Healthy Adults With and Without Androgenetic Alopecia
Androgenetic alopecia (AGA)Healthy Volunteers - Male and Female
Absci Pty Ltd.227 enrolled4 locationsNCT07317544
Recruiting
Phase 1
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Healthy VolunteersOverweight or Obesity
Hoffmann-La Roche30 enrolled2 locationsNCT07499050
Recruiting
Phase 1
A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together
Healthy Volunteers
Otsuka Pharmaceutical Development & Commercialization, Inc.48 enrolled1 locationNCT07446400
Recruiting
Phase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
Healthy VolunteerOlder Adults (65-85 Years)
University of Colorado, Denver40 enrolled6 locationsNCT07516405
Recruiting
Phase 1Phase 2
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679
Recruiting
Phase 1
A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old
Healthy Volunteer
Biogen78 enrolled1 locationNCT07133828
Recruiting
Phase 1
A Trial to Assess Safety, Tolerability, and Pharmacokinetics of AN01 Inhalation Powder in Healthy Participants
Healthy VolunteerHealthy Participants Study
AirNexis Therapeutics, Inc.24 enrolled1 locationNCT07554365
Recruiting
Phase 1
Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
Non-small Cell Lung Cancer (NSCLC)Ovarian CancerCervical Cancer+4 more
Radiopharm Theranostics, Ltd9 enrolled2 locationsNCT05799274
Recruiting
Phase 1
Drug-Drug Interaction Study of Atumelnant in Healthy Participants
Healthy Volunteers
Crinetics Pharmaceuticals Inc.46 enrolled1 locationNCT07570082
Recruiting
Phase 1
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
Healthy Volunteers
AbbVie12 enrolled1 locationNCT07567781
Recruiting
Phase 1
A Study of BGM0504 Tablets in Healthy Chinese Subjects
Chinese Healthy Volunteers
BrightGene Bio-Medical Technology Co., Ltd.144 enrolled1 locationNCT07566572
Recruiting
Phase 1Phase 2
Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause
Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled13 locationsNCT07118891
Recruiting
Phase 1
The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.
Healthy Volunteers
Bloodworks12 enrolled1 locationNCT07513532
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics of GenSci161 in Healthy Adult Participants
Healthy Volunteers
Changchun GeneScience Pharmaceutical Co., Ltd.44 enrolled1 locationNCT07476586
Recruiting
Phase 1
Study of the Safety, Tolerability, Pharmacokinetics of VV913 Capsules in Chinese Healthy Participants
Healthy Volunteers
Vigonvita Life Sciences56 enrolled1 locationNCT07372703
Recruiting
Phase 1Phase 2
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1
A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55
Healthy Volunteer
Biogen70 enrolled1 locationNCT07297199
Recruiting
Phase 1
A Phase 1 Study to Assess the Effect of ABBV-722 on Ethinyl Estradiol and Levonorgestrel Drug Levels in Healthy Adult Female Participants
Healthy Volunteer
AbbVie16 enrolled1 locationNCT07502417
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 1
A Dose-Escalation Study of RO7875913 in Healthy Participants
Healthy Volunteers
Genentech, Inc.40 enrolled1 locationNCT07342114