Volunteer Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Volunteer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 315 trials

Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 2

Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Not Applicable

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

Healthy Volunteer
National Institute on Aging (NIA)180 enrolled1 locationNCT06274749
Recruiting

Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

Urothelial CancerBladder CancerHealthy Volunteers+1 more
National Cancer Institute (NCI)500 enrolled1 locationNCT02379429
Recruiting
Phase 1Phase 2

Study Evaluating ABCL635 for Vasomotor Symptoms of Menopause

Healthy VolunteersVasomotor Symptoms Associated With Menopause
AbCellera Biologics Inc.136 enrolled10 locationsNCT07118891
Recruiting
Phase 1

A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants

Healthy Volunteers
Genentech, Inc.48 enrolled2 locationsNCT07329972
Recruiting

Characterization of Diseases With Salivary Gland Involvement

Healthy VolunteerSjogren's SyndromeSalivary Gland Disease
National Institute of Dental and Craniofacial Research (NIDCR)1,150 enrolled1 locationNCT02327884
Recruiting

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Healthy VolunteersFrailNon-Healthy/Non-Frail
National Institute on Aging (NIA)900 enrolled1 locationNCT02339012
Recruiting

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

Healthy VolunteerImmunosuppressionPeriodontal Disease+1 more
National Institute of Dental and Craniofacial Research (NIDCR)700 enrolled1 locationNCT01568697
Recruiting
Not Applicable

Mechanism of Non-invasive Magnetic Stimulation

Healthy Volunteers
National Institute on Drug Abuse (NIDA)70 enrolled1 locationNCT03394066
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting
Not Applicable

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)700 enrolled1 locationNCT03258580
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled2 locationsNCT06845202
Recruiting
Not Applicable

Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery

Healthy Volunteer
Centre Hospitalier Universitaire de Saint Etienne33 enrolled1 locationNCT06845176
Recruiting
Phase 1

A Study to Evaluate ALN-4285 in Adult Healthy Volunteers

Healthy Volunteers
Alnylam Pharmaceuticals76 enrolled1 locationNCT07295717
Recruiting

Imaging Techniques in MRI

HealthyHealthy VolunteersCardiac Risk Factors
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT01130545
Recruiting
Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Healthy VolunteersOverweight
National Institute on Alcohol Abuse and Alcoholism (NIAAA)150 enrolled1 locationNCT03407079
Recruiting

Normal Values in Hearing and Balance Testing

Healthy Volunteer
National Institute on Deafness and Other Communication Disorders (NIDCD)500 enrolled1 locationNCT01629108
Recruiting

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Healthy VolunteersEndothelial DysfunctionInflammation in Cardiopulmonary and Vascular Disease States
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT03253705
Recruiting
Phase 1

A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)

Rheumatoid ArthritisHealthy VolunteersSystemic Lupus Erythematosus
Capstan Therapeutics64 enrolled1 locationNCT06917742