Volunteer Clinical Trials

415 recruitingLast updated: July 25, 2026

There are 415 actively recruiting volunteer clinical trials across 53 countries. Studies span Phase 1, Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Bethesda, Maryland, United States, Baltimore, Maryland, United States, Grayslake, Illinois, United States. Updated daily from ClinicalTrials.gov.


Volunteer Trials at a Glance

415 actively recruiting trials for volunteer are listed on ClinicalTrialsFinder across 6 cities in 53 countries. The largest study group is Phase 1 with 208 trials, with the heaviest enrollment activity in Bethesda, Baltimore, and Grayslake. Lead sponsors running volunteer studies include AbbVie, Bristol-Myers Squibb, and Centre Hospitalier Universitaire de Saint Etienne.

Treatments under study

About Volunteer Clinical Trials

Looking for clinical trials for Volunteer? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Volunteer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Volunteer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 415 trials

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Not Applicable

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)700 enrolled1 locationNCT03258580
Recruiting
Not Applicable

Analytical Validation of Circulating DNA Analysis Methods: Creation of a Control Cohort

Healthy Volunteers (Cancer)
Institut Claudius Regaud68 enrolled1 locationNCT07663994
Recruiting

Physical and Behavioral Traits of Overweight and Obese Adults

ObesityHealthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00428987
Recruiting
Phase 1Phase 2

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled87 locationsNCT06649110
Recruiting
Not Applicable

Neural and Psychological Mechanisms of Pain Perception

PainHealthy VolunteersNormal Physiology
National Center for Complementary and Integrative Health (NCCIH)550 enrolled1 locationNCT02446262
Recruiting

Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers

Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)1,000 enrolled1 locationNCT00442195
Recruiting

Tissue Procurement for Biomedical Research

Normal Volunteers
National Institute on Aging (NIA)5,000 enrolled1 locationNCT00182858
Recruiting
Not Applicable

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

Healthy Volunteer
National Institute on Aging (NIA)180 enrolled1 locationNCT06274749
Recruiting

Collection of Data and Samples From Healthy Donors for Use in Translational Research

Healthy Volunteer
National Institute of Allergy and Infectious Diseases (NIAID)150 enrolled1 locationNCT00090662
Recruiting
Phase 1

Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

Healthy VolunteersDengueHuman Challenge Trial
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled1 locationNCT07706686
Recruiting
Phase 1

Study Evaluating Safety & Tolerability of Migaldendranib in Healthy Volunteers

Healthy Volunteers
Ashvattha Therapeutics, Inc.36 enrolled1 locationNCT07370155
Recruiting
Phase 1

A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 Diabetes

Healthy VolunteerType 2 Diabetes
Novo Nordisk A/S60 enrolled1 locationNCT07270731
Recruiting

Characterization of Diseases With Salivary Gland Involvement

Healthy VolunteerSjogren's SyndromeSalivary Gland Disease
National Institute of Dental and Craniofacial Research (NIDCR)1,150 enrolled1 locationNCT02327884
Recruiting
Phase 1

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

Non-small Cell Lung Cancer (NSCLC)Ovarian CancerCervical Cancer+4 more
Radiopharm Theranostics, Ltd9 enrolled2 locationsNCT05799274
Recruiting
Phase 1

Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone

Healthy Volunteer Study
Atea Pharmaceuticals, Inc.32 enrolled3 locationsNCT07314346
Recruiting
Phase 1

A Study of B-3E07 and Forsteo® in Healthy Adult Female Participants

Healthy Volunteers
Syneos Health48 enrolled1 locationNCT07497503
Recruiting

Studies of Blood Flow to the Brain During Thought

Healthy Volunteer
National Institute of Mental Health (NIMH)4,100 enrolled1 locationNCT00001360
Recruiting
Phase 2

Neurobiology of Suicide

DepressionHealthy Volunteers
National Institute of Mental Health (NIMH)325 enrolled1 locationNCT02543983
Recruiting
Phase 1

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301