Von Willebrand Disease Clinical Trials

2 recruitingLast updated: May 5, 2026

Von Willebrand Disease Trials at a Glance

17 actively recruiting trials for von willebrand disease are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Phase 3 with 3 trials, with the heaviest enrollment activity in Seattle, Atlanta, and Aurora. Lead sponsors running von willebrand disease studies include American Thrombosis and Hemostasis Network, Hoffmann-La Roche, and Bleeding and Clotting Disorders Institute Peoria, Illinois.

Browse von willebrand disease trials by phase

Treatments under study

About Von Willebrand Disease Clinical Trials

Looking for clinical trials for Von Willebrand Disease? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Von Willebrand Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Von Willebrand Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

Von Willebrand Disease, Type 3
Hoffmann-La Roche75 enrolled27 locationsNCT06998524
Recruiting

ATHNdataset Registry

ThrombosisSickle Cell DiseaseHemophilia A+6 more
American Thrombosis and Hemostasis Network200,000 enrolled1 locationNCT06820515
Recruiting

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Von Willebrand Disease, Type 3
Hoffmann-La Roche40 enrolled27 locationsNCT06883240
Recruiting

Development of a Device for Evaluating Primary Hemostasis Under Whole Blood Flow Conditions

Von Willebrand DiseasesMajor Constitutional ThrombopathyPatient on Antiplatelet Drugs
Centre Hospitalier Universitaire Dijon200 enrolled2 locationsNCT03773159
Recruiting
Phase 1

Emicizumab for Severe Von Willebrand Disease (VWD) and VWD/Hemophilia A

Von Willebrand Disease, Type 3Concomitant VWD and Hemophilia
Bleeding and Clotting Disorders Institute Peoria, Illinois40 enrolled12 locationsNCT05500807
Recruiting

An Observational Study of Vonicog Alfa (rVWF) in Pediatric Participants With Von Willebrand Disease (vWD)

Von Willebrand Disease (vWD)
Takeda13 enrolled1 locationNCT07404644
Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

ThrombophiliaThrombosisSickle Cell Disease+10 more
American Thrombosis and Hemostasis Network3,000 enrolled71 locationsNCT04398628
Recruiting

Von Willebrand Factor in Pregnancy (VIP) Study

Von Willebrand Diseases
University of Washington110 enrolled11 locationsNCT04146376
Recruiting

Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study

Bleeding DisorderHeavy Menstrual BleedingVon Willebrand Diseases
Oregon Health and Science University300 enrolled9 locationsNCT05916469
Recruiting
Phase 2

Efficacy and Safety of BT200 (Rondaptivon Pegol) in Patients With Type 2B Von Willebrand Disease

Von Willebrand Disease (VWD), Type 2
Medical University of Vienna6 enrolled1 locationNCT07273721
Recruiting
Phase 1Phase 2

Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

Von Willebrand Diseases
Vega Therapeutics, Inc116 enrolled25 locationsNCT05776069
Recruiting
Phase 3

A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

Von Willebrand Disease
Baxalta now part of Shire31 enrolled46 locationsNCT02932618
Recruiting

Cardiovascular and Venous Thromboembolism Disease in Patients with Von Willebrand Disease in the French West

Von Willebrand Diseases
University Hospital, Brest100 enrolled6 locationsNCT05773638
Recruiting
Phase 3

A Pilot Crossover Trial of Prophylactic Wilate Compared to Placebo for Heavy Menstrual Bleeding in Patients with VWD

Von Willebrand Diseases
Unity Health Toronto20 enrolled1 locationNCT06205095
Recruiting
Phase 4

Efficacy and Safety of Fanhdi®, a High-purity Von Willebrand Containing FVIII Concentrate, in Pediatric Patients With Von Willebrand Disease

Von Willebrand Disease
Grifols Therapeutics LLC8 enrolled4 locationsNCT02472665
Recruiting
Not Applicable

Videomicroscopy for the Prediction of Bleeding in Constitutional Haemorrhagic Diseases

Von Willebrand DiseasesGlanzmann Thrombasthenia
University Hospital, Lille400 enrolled1 locationNCT04119908
Recruiting

World Bleeding Disorders Registry

Hemophilia AHemophilia BVon Willebrand Diseases
World Federation of Hemophilia20,000 enrolled1 locationNCT03327779