Brigham and Women's Hospital
Boston, Massachusetts, United States
150 recruiting
Showing 1–20 of 364 trials
Recruiting
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
Genetic Disease
National Human Genome Research Institute (NHGRI)20,000 enrolled33 locationsNCT02450851
Recruiting
Phase 2
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Metastatic Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8+1 more
NRG Oncology240 enrolled328 locationsNCT05327686
Recruiting
Phase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
COVID-19
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled6 locationsNCT07536308
Recruiting
Phase 2
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change
Recurrent Lung Non-Small Cell CarcinomaAdvanced Lung Non-Small Cell CarcinomaStage IIIB Lung Non-Small Cell Cancer AJCC v7+1 more
National Cancer Institute (NCI)46 enrolled345 locationsNCT03191149
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Moderately to Severely Active Crohns Disease
Hoffmann-La Roche600 enrolled372 locationsNCT06819878
Recruiting
Phase 3
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
Interstitial Lung DiseasesSystemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Boehringer Ingelheim400 enrolled156 locationsNCT06806592
Recruiting
Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmImmune System Disorder
Alliance for Clinical Trials in Oncology2,240 enrolled625 locationsNCT04242095
Recruiting
Phase 4
Statins to Prevent Cancer Associated Blood Clots
CancerVenous ThromboembolismCardiovascular Events
Brigham and Women's Hospital4,000 enrolled2 locationsNCT07303816
Recruiting
Phase 3
A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)
Immunoglobulin A Nephropathy (IgAN)
Biogen454 enrolled251 locationsNCT06935357
Recruiting
Not Applicable
Accelerated TMS for Perinatal Depression
Major Depressive DisorderPerinatal DepressionPost Partum Depression
Brigham and Women's Hospital24 enrolled1 locationNCT06968390
Recruiting
Not Applicable
Alleviant ALLAY-HFrEF Study
Heart Failure
Alleviant Medical, Inc.350 enrolledNCT06812533
Recruiting
Not Applicable
Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral Pharyngeal Collapse
Obstructive Sleep ApneaSleep-Disordered Breathing
Brigham and Women's Hospital72 enrolledNCT07724938
Recruiting
Phase 1Phase 2
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
Metastatic Renal Cell CarcinomaCarcinoma, Renal CellAdvanced Renal Cell Carcinoma+10 more
Pfizer224 enrolled128 locationsNCT07227415
Recruiting
Phase 2
EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Diffuse Cutaneous Systemic Sclerosis
Mediar Therapeutics85 enrolled6 locationsNCT07287670
Recruiting
Phase 3
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
Venous Thromboembolism (VTE)
Regeneron Pharmaceuticals2,000 enrolled46 locationsNCT07015905
Recruiting
Not Applicable
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Mitral Valve Regurgitation
Medtronic Cardiovascular1,056 enrolled85 locationsNCT03242642
Recruiting
Phase 2
ALPINE: Maintenance Letrozole/Abemaciclib
Endometrial CancerTP53Recurrent Endometrial Cancer
Dana-Farber Cancer Institute32 enrolled6 locationsNCT06366347
Recruiting
Not Applicable
Effect of Physical Activity Pattern on Cardiometabolic Health
Life Style
Brigham and Women's Hospital26 enrolled1 locationNCT05838508
Recruiting
Phase 1Phase 2
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
seizureEpilepsyDrug Resistant Epilepsy+2 more
NaviFUS Corporation8 enrolled3 locationsNCT06388707
Recruiting
A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab
Recurrent Mycosis FungoidesRecurrent Sezary SyndromeRefractory Mycosis Fungoides+6 more
City of Hope Medical Center100 enrolled10 locationsNCT07003100