Brigham and Women's Hospital
Boston, Massachusetts, United States
150 recruiting
Showing 1–20 of 349 trials
Recruiting
Phase 1Phase 2
Low Dose IL-2 for the Treatment of Crohn's Disease
Crohn Disease
Boston Children's Hospital30 enrolled3 locationsNCT04263831
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
MelanomaNon-small Cell Lung CancerThyroid Cancer+2 more
Pfizer267 enrolled40 locationsNCT05355701
Recruiting
Phase 2
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change
Recurrent Lung Non-Small Cell CarcinomaAdvanced Lung Non-Small Cell CarcinomaStage IIIB Lung Non-Small Cell Cancer AJCC v7+1 more
National Cancer Institute (NCI)46 enrolled345 locationsNCT03191149
Recruiting
Phase 3
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
COVID-19 (SARS-CoV-2) infection
Pfizer2,330 enrolled253 locationsNCT06679140
Recruiting
Phase 1
A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults
COVID-19
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled6 locationsNCT07536308
Recruiting
The Oxford Risk Factors And Non-Invasive Imaging Study
Cardiovascular DiseasesCardiovascular Risk Factors
University of Oxford250,000 enrolled45 locationsNCT05169333
Recruiting
Phase 2
LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Pulmonary Hypertension Due to Lung Diseases and Hypoxia
OrphAI Therapeutics85 enrolled3 locationsNCT05798923
Recruiting
Not Applicable
FORWARD CAD IDE Study
Coronary Arterial Disease (CAD)
Shockwave Medical, Inc.408 enrolled34 locationsNCT06662500
Recruiting
Not Applicable
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
Coronary Arterial Disease (CAD)de Novo Lesions in Native Coronary Arteries
Boston Scientific Corporation1,616 enrolled67 locationsNCT06959524
Recruiting
Phase 2
A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo
VitiligoNon-Segmental Vitiligo (NSV)
Eli Lilly and Company66 enrolled35 locationsNCT07533019
Recruiting
Phase 3
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
COVID-19 Infection
Pfizer300 enrolled152 locationsNCT07013474
Recruiting
Phase 2
RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
Prostate CancerProstatic Neoplasms
Dana-Farber Cancer Institute110 enrolled3 locationsNCT05765500
Recruiting
Phase 1
Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria
ProteinuriaProteinuric Kidney DiseaseProteinuric Renal Disease+1 more
Brigham and Women's Hospital20 enrolled1 locationNCT07224776
Recruiting
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
Ulcerative Colitis (UC)Inflammatory Bowel Disease (IBD)Indeterminate Colitis+1 more
University of North Carolina, Chapel Hill200 enrolled10 locationsNCT07237516
Recruiting
Phase 2
PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC
Head and Neck CancerHead and Neck Squamous Cell CarcinomaMetastatic Head and Neck Squamous Cell Carcinoma+3 more
Dana-Farber Cancer Institute25 enrolled2 locationsNCT06239220
Recruiting
Phase 1
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled83 locationsNCT05538130
Recruiting
Phase 1
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Metastatic Castration-resistant Prostate Cancer (mCRPC)Small Cell Lung Cancer ( SCLC )Follicular Lymphoma ( FL)
Pfizer453 enrolled82 locationsNCT03460977
Recruiting
Phase 1
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
Hematopoietic and Lymphatic System NeoplasmAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+9 more
City of Hope Medical Center46 enrolled3 locationsNCT07020533
Recruiting
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
Genetic Disease
National Human Genome Research Institute (NHGRI)20,000 enrolled33 locationsNCT02450851
Recruiting
Phase 2
Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
Breast CarcinomaEstrogen Receptor-Positive Breast CarcinomaBreast Ductal Carcinoma in Situ+3 more
National Cancer Institute (NCI)200 enrolled11 locationsNCT06184750