Centre for Addiction and Mental Health

Toronto, Ontario, Canada

31 recruiting

Showing 120 of 55 trials

Recruiting
Not Applicable

Digital Dialectical Behavioural Therapy (d-DBT) for Youth at Clinical High Risk (CHR) for Psychosis

Clinical High Risk for Psychosis (CHR)
Centre for Addiction and Mental Health60 enrolledNCT06928935
Recruiting
Phase 4

Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health30 enrolled1 locationNCT02639702
Recruiting
Not Applicable

Left vs. Right Non-Inferiority Trial

DepressionMajor Depressive DisorderMajor Depressive Episode
University of British Columbia480 enrolledNCT04999553
Recruiting
Phase 2

Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression

Treatment Resistant Depression
Centre for Addiction and Mental Health40 enrolled2 locationsNCT07211438
Recruiting
Not Applicable

Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial

Major Depressive Disorder
Centre for Addiction and Mental Health300 enrolled1 locationNCT05142683
Recruiting
Phase 4

Biomarkers to Enhance Early Schizophrenia Treatment

Schizophenia Disorder
Northwell Health180 enrolled5 locationsNCT06969755
Recruiting
Phase 2

Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)

Chronic PainTreatment Resistant Depression
Centre for Addiction and Mental Health16 enrolled1 locationNCT06518720
Recruiting
Phase 2

Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)

Treatment Resistant Depression
Centre for Addiction and Mental Health12 enrolled1 locationNCT06512220
Recruiting
Phase 2

Cannabidiol Medication Intervention Trial

Alzheimer Disease
Sunnybrook Health Sciences Centre40 enrolled5 locationsNCT06014424
Recruiting

An Innovative Master Platform for Clinical Trials in Mood Disorders

Depressive DisorderMood DisordersBipolar and Related Disorders
St. Joseph's Healthcare Hamilton2,200 enrolled9 locationsNCT06408012
Recruiting
Not Applicable

THC Titration of High-Potency Cannabis Concentrates

THC
Centre for Addiction and Mental Health48 enrolled1 locationNCT07105449
Recruiting
Phase 4

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Major Depressive Disorder
Nova Scotia Health Authority400 enrolled10 locationsNCT05017311
Recruiting
Not Applicable

Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

HealthySchizophrenia
Centre for Addiction and Mental Health20 enrolled1 locationNCT05748990
Recruiting
Phase 4

"Extended" (Alternate Day) Antipsychotic Dosing

Drug TherapySchizophrenia and Related DisordersAntipsychotic Agents+1 more
Centre for Addiction and Mental Health120 enrolled1 locationNCT04478838
Recruiting
Not Applicable

TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)

Mild Cognitive Impairment (MCI)
Centre for Addiction and Mental Health20 enrolled1 locationNCT06783283
Recruiting
Phase 4

Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?

CognitionHealthy (Controls)Brain Insulin-sensitivity
Centre for Addiction and Mental Health35 enrolled1 locationNCT07109245
Recruiting
Not Applicable

Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder

Cannabis Use Disorder
Centre for Addiction and Mental Health46 enrolled1 locationNCT05859347
Recruiting
Phase 4

Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability

ObesityDevelopmental DisabilityIntellectual Disability
Centre for Addiction and Mental Health100 enrolled1 locationNCT05744479
Recruiting
Not Applicable

Effects of NAC on Symptoms of CHR Patients

Prodromal Schizophrenia
Centre for Addiction and Mental Health90 enrolled1 locationNCT05142735
Recruiting
Phase 1

Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD

Obsessive-Compulsive Disorder
Centre for Addiction and Mental Health10 enrolled1 locationNCT06299319