Karolinska Universitetssjukhuset

Stockholm, Sweden

15 recruiting

Showing 120 of 23 trials

Recruiting
Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

Alzheimer s Disease
Hoffmann-La Roche50 enrolled6 locationsNCT07234942
Recruiting
Phase 3

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

Focal Segmental Glomerulosclerosis
Boehringer Ingelheim286 enrolled256 locationsNCT07220083
Recruiting

Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes

InfertilityMicrobiomePregnancy Complications+3 more
Karolinska Institutet1,000 enrolled3 locationsNCT07532629
Recruiting

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Relapsed Refractory Multiple Myeloma (RRMM)
Janssen-Cilag Ltd.900 enrolled68 locationsNCT06285318
Recruiting
Phase 2

A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

Adenocarcinoma, Pancreatic Ductal
Genentech, Inc.260 enrolled89 locationsNCT05968326
Recruiting
Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled234 locationsNCT06662786
Recruiting
Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled234 locationsNCT06750094
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Solid TumorsHGGCancer Harboring BRAF Alterations+1 more
Fore Biotherapeutics254 enrolled67 locationsNCT05503797
Recruiting
Phase 3

Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)

Metastatic Castration-resistant Prostate Cancer
Amgen675 enrolled164 locationsNCT06691984
Recruiting
Phase 3

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

Advanced Melanoma
Immunocore Ltd680 enrolled211 locationsNCT06112314
Recruiting

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

IGF1 Deficiency
Esteve Pharmaceuticals, S.A.500 enrolled58 locationsNCT00903110
Recruiting
Phase 3

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

Cancer
Bayer402 enrolled383 locationsNCT04464226
Recruiting
Phase 2

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)

Dedifferentiated Liposarcoma
Lund University Hospital33 enrolled4 locationsNCT06389799
Recruiting
Phase 3

MYTHS - MYocarditis THerapy With Steroids

Myocarditis Acute
Niguarda Hospital288 enrolled49 locationsNCT05150704
Recruiting
Phase 4

Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

AsthmaInflammation
St. Olavs Hospital280 enrolled8 locationsNCT03889743
Recruiting
Not Applicable

Leadership for Recovery: Evaluation of an Intervention Programme for First-line Healthcare Managers

InsomniaSleepFatigue+3 more
Karolinska Institutet960 enrolled2 locationsNCT06678347
Recruiting
Phase 3

Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation

DeathAtrial FibrillationChronic Kidney Diseases+6 more
Region Stockholm1,400 enrolled34 locationsNCT05679024
Recruiting
Not Applicable

Direct or Subacute Coronary Angiography in Out-of-hospital Cardiac Arrest

Uppsala University1,006 enrolled21 locationsNCT02309151
Recruiting
Phase 2

Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy

Radiotherapy Side EffectCognitive ImpairmentBrain Tumor+4 more
Region Stockholm84 enrolled2 locationsNCT06051240
Recruiting

Biological Mechanisms Behind Resynchronization Therapy in Heart Failure

Heart FailureCardiac Remodeling, Ventricular
Region Stockholm220 enrolled1 locationNCT06140914