Karolinska University Hospital

Stockholm, Sweden

82 recruiting

Showing 120 of 170 trials

Recruiting
Phase 3

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic CancerAdvanced Gastrointestinal Stromal Tumors
Cogent Biosciences, Inc.482 enrolled126 locationsNCT05208047
Recruiting
Phase 3

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting
Phase 1Phase 2

Safety and Performance of a Novel Infusion Catheter System for Peri/Intratumoral Gemcitabine Delivery in Patients With Pancreatic Cancer

Pancreatic Cancer Non-resectable
Smartwise Sweden AB9 enrolled1 locationNCT07575191
Recruiting
Phase 3

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Kidney Disease, Chronic
Boehringer Ingelheim11,000 enrolled475 locationsNCT06531824
Recruiting
Phase 3

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

Bronchiectasis
Boehringer Ingelheim1,755 enrolled494 locationsNCT06872892
Recruiting
Not Applicable

Evaluation of a Psychosocial Support Model for Adolescents and Young Adults Newly Diagnosed With Cancer

Cancer
Karolinska Institutet142 enrolled2 locationsNCT06979843
Recruiting
Phase 1Phase 2

Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC

PDAC
Anocca AB96 enrolled10 locationsNCT07145450
Recruiting

Dementia With Lewy Bodies: Clinical Symptoms, Biomarkers and Progression

Mild Cognitive Impairment (MCI)Other DementiasCognitively Unimpaired+1 more
Karolinska Institutet600 enrolled1 locationNCT07629349
Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled179 locationsNCT05457283
Recruiting

Soft Tissue Radiation Injury; Patient Reported Evaluation in a Single Centre Cohort Study (STRIPE)

Radiation ProctitisSoft Tissue Radionecrosis (STRN)Cystitis, Radio Induced
Karolinska University Hospital1,000 enrolled1 locationNCT07611864
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

Acromegaly
Debiopharm International SA119 enrolled71 locationsNCT06930625
Recruiting
Phase 2

Prostate Androgen Response Investigation Using a Stratification BIOmarker; Predicting Prostate Cancer Downstaging by Neoadjuvant Darolutamide With PCAI ImmunoScore

Prostate Cancer (Adenocarcinoma)
Region Stockholm100 enrolled2 locationsNCT07617272
Recruiting
Phase 1Phase 2

Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma

Carcinoma, Renal Cell
Oncorena AB75 enrolled5 locationsNCT05287945
Recruiting
Phase 3

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer
BioNTech SE480 enrolled156 locationsNCT06340568
Recruiting
Not Applicable

The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.

Heart Valve DiseaseInfective Endocarditis (IE)
Region Skane1,300 enrolled5 locationsNCT07511673
Recruiting

Physical Activity in Persons With Parkinson's Disease

Sedentary behaviorsPhysical ActivityPARKINSON DISEASE (Disorder)
Karolinska Institutet450 enrolled1 locationNCT07585409
Recruiting
Phase 3

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Myelodysplastic Syndromes
Takeda225 enrolled179 locationsNCT06499285
Recruiting

Natural History of Type 1 Interferonopathies: Insights From a European Cohort

Genetic DiseaseAutoimmune DiseasesNeurological Diseases or Conditions+1 more
Imagine Institute500 enrolled32 locationsNCT07040774
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390
Recruiting

Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery

Acute Kidney Injury
Uppsala University2,000 enrolled13 locationsNCT07351149