London Health Sciences Centre

London, Ontario, Canada

50 recruiting

Showing 120 of 110 trials

Recruiting
Phase 3

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer
Incyte Corporation466 enrolled157 locationsNCT07214779
Recruiting
Phase 3

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

Leukemia
Daiichi Sankyo700 enrolled288 locationsNCT06578247
Recruiting
Phase 2

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

Pulmonary Hypertension
Pfizer36 enrolled44 locationsNCT07073820
Recruiting
Phase 3

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Phase 3

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer
Stemline Therapeutics, Inc.4,220 enrolled536 locationsNCT06492616
Recruiting
Phase 1Phase 2

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Solid Tumor
Novartis Pharmaceuticals222 enrolled40 locationsNCT04939610
Recruiting
Phase 3

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Chronic Lymphocytic LeukemiaCLL
BeOne Medicines250 enrolled115 locationsNCT06846671
Recruiting
Phase 2

Belimumab in Autoimmune Hepatitis

Autoimmune Hepatitis
University Health Network, Toronto48 enrolled5 locationsNCT06381453
Recruiting
Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Marginal Zone LymphomaRelapsed/Refractory Follicular Lymphoma
BeiGene780 enrolled277 locationsNCT05100862
Recruiting
Phase 2

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative ColitisUlcerative Colitis Chronic
Eli Lilly and Company140 enrolled207 locationsNCT06598943
Recruiting
Phase 3

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled66 locationsNCT04844606
Recruiting
Phase 2

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Inflammatory Bowel DiseasesCrohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)385 enrolled215 locationsNCT06226883
Recruiting
Early Phase 1

Oral Carnitine in Heart Failure Patients

Heart FailureCarnitine Deficiency
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled1 locationNCT07201714
Recruiting
Phase 2

Study to Evaluate the Effects of AV-001 on HD-induced Brain Injury.

Hemodialysis
London Health Sciences Centre Research Institute60 enrolled1 locationNCT07234890
Recruiting
Phase 3

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

GliomaH3 K27M
Jazz Pharmaceuticals510 enrolled162 locationsNCT05580562
Recruiting

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

Pain
Boston Scientific Corporation4,800 enrolled118 locationsNCT01719055
Recruiting
Phase 1

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

ALS
Amylyx Pharmaceuticals Inc.48 enrolled14 locationsNCT06665165
Recruiting
Not Applicable

Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation

Alp Sener120 enrolled1 locationNCT06288152
Recruiting
Not Applicable

Online Prehabilitation for Patients Awaiting Liver Transplantation

Liver Transplant SurgeryCirrhosis, LiverLiver Disease
University of Alberta177 enrolled6 locationsNCT05899231
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199