Royal Free Hospital
London, United Kingdom
23 recruiting
Showing 1–20 of 23 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Breast CancerLung Cancer
Bristol-Myers Squibb416 enrolled63 locationsNCT06618287
Recruiting
Not Applicable
WATER IV Prostate Cancer
Localized Prostate Cancer
PROCEPT BioRobotics280 enrolled36 locationsNCT06651632
Recruiting
Phase 1Phase 2
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
Advanced Solid Tumor
BioNTech SE980 enrolled53 locationsNCT07070232
Recruiting
Phase 3
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Breast Cancer
Hoffmann-La Roche450 enrolled210 locationsNCT06790693
Recruiting
Phase 1Phase 2
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Metastatic Breast CancerColorectal, CancerEsophageal Adenocarcinoma+2 more
Boehringer Ingelheim768 enrolled103 locationsNCT06324357
Recruiting
Not Applicable
RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure
Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069
Recruiting
Phase 1
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer
Hoffmann-La Roche542 enrolled73 locationsNCT04929223
Recruiting
Phase 3
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Metastatic Colorectal Cancer
Amgen450 enrolled284 locationsNCT06252649
Recruiting
Phase 1Phase 2
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
Metastatic Breast CancerLocally Advanced Breast CancerUnresectable Breast Carcinoma
BioNTech SE380 enrolled20 locationsNCT06827236
Recruiting
Phase 2
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
SclerodermaSystemic Sclerosis (SSc)
Zura Bio Inc80 enrolled51 locationsNCT06843239
Recruiting
Phase 1Phase 2
EMITT-1 (ERAP Mediated Immunopeptidome Targeting Trial - 1)
Advanced Solid Malignancy
Grey Wolf Therapeutics300 enrolled29 locationsNCT06923761
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 3
A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer
Prostate Cancer Metastatic
University College, London3,360 enrolled18 locationsNCT06320067
Recruiting
Phase 2
Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer
Pancreatic Cancer
Cambridge University Hospitals NHS Foundation Trust20 enrolled13 locationsNCT05093231
Recruiting
Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis
Liver CirrhosisDecompensated Cirrhosis of Liver
European Foundation for Study of Chronic Liver Failure189 enrolled9 locationsNCT06855056
Recruiting
DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution
Lung CancerPulmonary Nodule, SolitaryAI (Artificial Intelligence)+1 more
Nottingham University Hospitals NHS Trust2,000 enrolled10 locationsNCT05389774
Recruiting
Non-contact Proactive Remote Monitoring of COPD Exacerbations
COPD Exacerbation
Life Detection Technologies75 enrolled1 locationNCT05598983
Recruiting
Phase 2
Perioperative Pembrolizumab and Lenvatinib in Resectable Hepatocellular Carcinoma (HCC)
Hepatocellular Carcinoma
University College, London60 enrolled11 locationsNCT05185739
Recruiting
Phase 3
A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT
Prostate Cancer
Institute of Cancer Research, United Kingdom1,128 enrolled42 locationsNCT05613023
Recruiting
Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer
Colorectal, Cancer
Royal Marsden NHS Foundation Trust1,000 enrolled71 locationsNCT04050345