The Ottawa Hospital

Ottawa, Ontario, Canada

29 recruiting

Showing 120 of 83 trials

Recruiting
Phase 3

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Kidney Disease, Chronic
Boehringer Ingelheim11,000 enrolled452 locationsNCT06531824
Recruiting

International Severe Asthma Registry: Canadian Cohort

Severe Asthma
University of British Columbia714 enrolled12 locationsNCT04045587
Recruiting

Variability and Post-op AEs: Does Preoperative CardioPulmonary Variability Assessment Identify Risk of Postoperative Adverse Events Following Thoracic Surgery

Thoracic CancerComplication,Postoperative
Ottawa Hospital Research Institute130 enrolled1 locationNCT07016022
Recruiting

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

Huntington’s Disease
University College, London2,500 enrolled40 locationsNCT02855476
Recruiting
Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
BeOne Medicines630 enrolled167 locationsNCT06943872
Recruiting
Phase 1

A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.

Charcot-Marie-Tooth Disease, Type 1A
Novartis Pharmaceuticals28 enrolled3 locationsNCT07140614
Recruiting
Phase 1

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Colorectal, CancerNon-small Cell Lung CancerPancreatic Ductal Adenocarcinoma
Eli Lilly and Company630 enrolled52 locationsNCT06586515
Recruiting
Phase 1

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Carcinoma, Non-Small Cell LungGastroesophageal Junction AdenocarcinomaStomach Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer914 enrolled44 locationsNCT06131840
Recruiting
Not Applicable

Liberation From Mechanical Ventilation Using Extubation Advisor Decision Support

Airway Extubation
Ottawa Hospital Research Institute200 enrolled12 locationsNCT05506904
Recruiting
Phase 3

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Community-acquired Pneumonia
University of Manitoba4,000 enrolled64 locationsNCT05848713
Recruiting
Not Applicable

BosSTENT Implantation to Treat Pulse-Synchronous Tinnitus

Venous Sinus StenosisPulsatile Tinnitus
Sonorous NV, Inc90 enrolled6 locationsNCT07070089
Recruiting
Phase 3

Canadian Critical Care Comparative Effectiveness Platform

NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled8 locationsNCT06605144
Recruiting
Phase 4

Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes

CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting
Not Applicable

Advanced Brain Imaging-TKA (fMRI-TKA)

Patient SatisfactionKnee Pain ChronicKnee Osteoarthritis (Knee OA)+2 more
Ottawa Hospital Research Institute50 enrolled1 locationNCT07464080
Recruiting
Phase 3

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

Open tíbia Fracture
University of Maryland, Baltimore312 enrolled33 locationsNCT05615844
Recruiting
Not Applicable

INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients

Soft Tissue SarcomaWound Complication
Dr. J. Werier291 enrolled2 locationsNCT03175718
Recruiting
Phase 2

Tucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility Study

HER2-positive Breast CancerLMD
Sunnybrook Health Sciences Centre30 enrolled2 locationsNCT06016387
Recruiting
Not Applicable

Platform of Randomized Adaptive Clinical Trials in Critical Illness

Respiratory InsufficiencyMechanical Ventilation Pressure HighExtracorporeal Membrane Oxygenation Complication
University Health Network, Toronto6,250 enrolled86 locationsNCT05440851
Recruiting

VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

Crohn's Disease
Alimentiv Inc.300 enrolled25 locationsNCT06249555
Recruiting
Not Applicable

A Platform Trial for Gram Negative Bloodstream Infections

Gram-negative Bacteremia
Sunnybrook Health Sciences Centre2,500 enrolled39 locationsNCT06537609