The Ottawa Hospital
Ottawa, Ontario, Canada
29 recruiting
Showing 1–20 of 85 trials
Recruiting
Phase 1
A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A.
Charcot-Marie-Tooth Disease, Type 1A
Novartis Pharmaceuticals28 enrolled3 locationsNCT07140614
Recruiting
Phase 3
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
BeOne Medicines630 enrolled192 locationsNCT06943872
Recruiting
Phase 3
A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD
facioscapulohumeral muscular dystrophyFascioscapulohumeral Muscular DystrophyFacio-Scapulo-Humeral Dystrophy+14 more
Avidity Biosciences, Inc.200 enrolled46 locationsNCT07038200
Recruiting
Phase 1Phase 2
Modafinil to Improve Fatiguability
Cancer-related Cognitive DifficultiesFatigueCancer-related Problem/Condition
Ottawa Hospital Research Institute40 enrolled1 locationNCT05333250
Recruiting
Phase 1
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Carcinoma, Non-Small Cell LungGastroesophageal Junction AdenocarcinomaStomach Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer914 enrolled48 locationsNCT06131840
Recruiting
Phase 3
Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism
Venous ThromboembolismGastro Intestinal BleedingBlood Clot
Ottawa Hospital Research Institute360 enrolled7 locationsNCT06393868
Recruiting
Phase 3
To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL
Peripheral T Cell Lymphoma
Acrotech Biopharma Inc.504 enrolled69 locationsNCT06072131
Recruiting
DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.
Liver CancerLiver Metastases
Maastricht University Medical Center350 enrolled31 locationsNCT07717437
Recruiting
Phase 3
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
Psychological Distress
Bruyère Health Research Institute.120 enrolled7 locationsNCT07063862
Recruiting
Phase 3
Canadian Critical Care Comparative Effectiveness Platform
NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled9 locationsNCT06605144
Recruiting
Phase 3
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Kidney Disease, Chronic
Boehringer Ingelheim11,000 enrolled480 locationsNCT06531824
Recruiting
Phase 3
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Breast CancerPain, ChronicPost-mastectomy Pain Syndrome+1 more
University Health Network, Toronto1,602 enrolled17 locationsNCT04874038
Recruiting
Phase 1
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Colorectal, CancerNon-small Cell Lung CancerPancreatic Ductal Adenocarcinoma
Eli Lilly and Company630 enrolled52 locationsNCT06586515
Recruiting
Surveillance of Complex Renal Cysts - The SOCRATIC Study
Complex Renal Cyst
Université de Sherbrooke330 enrolled18 locationsNCT04558593
Recruiting
Phase 4
Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer
Breast Cancer
Ottawa Hospital Research Institute500 enrolled8 locationsNCT04921137
Recruiting
Not Applicable
Evaluating XPERIENCE™ Advanced Surgical Irrigation
Knee Osteoarthritiship osteoarthritisHip Arthritis+1 more
Ottawa Hospital Research Institute7,600 enrolled8 locationsNCT05543941
Recruiting
Phase 4
Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled40 locationsNCT04263038
Recruiting
Not Applicable
Platform of Randomized Adaptive Clinical Trials in Critical Illness
Respiratory InsufficiencyMechanical Ventilation Pressure HighExtracorporeal Membrane Oxygenation Complication
University Health Network, Toronto6,250 enrolled89 locationsNCT05440851
Recruiting
Not Applicable
Pancreatic Insulin Production Capacity (PIPC) - a Feasibility Study
Type 2 Diabetes
Ottawa Hospital Research Institute90 enrolled1 locationNCT06462170
Recruiting
Phase 3
Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy
Open tíbia Fracture
University of Maryland, Baltimore312 enrolled34 locationsNCT05615844