Clinical Trials in Sheffield, South Yorkshire
40 recruiting
Showing 1–20 of 40 trials
Recruiting
Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)
FSHD
University of Kansas Medical Center450 enrolled21 locationsNCT04635891
Recruiting
Not Applicable
Utility of PET-MRI in Surveillance of Paediatric Brain Tumours
Brain Tumor, Pediatric
Sheffield Children's NHS Foundation Trust5 enrolled1 locationNCT05553899
Recruiting
Phase 3
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals360 enrolled99 locationsNCT06846281
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled85 locationsNCT06649110
Recruiting
Phase 3
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Generalized Myasthenia Gravis
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany264 enrolled133 locationsNCT06463587
Recruiting
Phase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences850 enrolled87 locationsNCT06966401
Recruiting
Phase 4
Is ICG Imaging Safe and Accurate to Predict Testicular Torsion?
Scrotum DiseaseTorsion Testis
Sheffield Children's NHS Foundation Trust107 enrolled1 locationNCT07545278
Recruiting
Phase 2
BAY3401016; Biomarker Study Alport
Alport Syndrome
Bayer60 enrolled60 locationsNCT07211685
Recruiting
Phase 1Phase 2
Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
Novartis Pharmaceuticals15 enrolled10 locationsNCT06704269
Recruiting
Phase 3
A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults
Influenza
ModernaTX, Inc.4,000 enrolled36 locationsNCT07496450
Recruiting
Phase 3
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Autosomal Dominant Polycystic Kidney Disease
The University of Queensland1,174 enrolled49 locationsNCT04939935
Recruiting
Not Applicable
Investigating the Tolerability and Feasibility of tVNS Following aSAH
Subarachnoid Haemorrhage From Cerebral Aneurism Rupture
Sheffield Teaching Hospitals NHS Foundation Trust30 enrolled1 locationNCT06374693
Recruiting
The Use of Advanced Imaging in HFpEF
Heart Failure With Preserved Ejection Fraction (HFpEF)
Sheffield Teaching Hospitals NHS Foundation Trust40 enrolled2 locationsNCT06905405
Recruiting
Phase 1
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Muscular Atrophy, Spinal
Biogen58 enrolled19 locationsNCT06555419
Recruiting
Not Applicable
Virtual Dietetic Interventions in Patients With Coeliac
coeliac disease
Sheffield Teaching Hospitals NHS Foundation Trust60 enrolled1 locationNCT07172555
Recruiting
Not Applicable
Efficacy of Symprove Probiotics in Coeliac Disease
Probioticcoeliac diseaseGluten
Sheffield Teaching Hospitals NHS Foundation Trust24 enrolled1 locationNCT07360106
Recruiting
Phase 3
A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old (BRAVE)
Friedreich Ataxia
Biogen255 enrolled34 locationsNCT06953583
Recruiting
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Atopic Dermatitis
Galderma R&D1,000 enrolled108 locationsNCT06988605
Recruiting
A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies
Muscular Atrophy, Spinal
Biogen20 enrolled14 locationsNCT05789758
Recruiting
Not Applicable
RCT of Implantable Defibrillators in Patients With Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure
Heart Failure
University Hospital Southampton NHS Foundation Trust2,504 enrolled47 locationsNCT05568069