Clinical Trials in Sylmar, California

21 recruiting

Showing 120 of 21 trials

Recruiting
Phase 3

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Endometrial Cancer
AstraZeneca600 enrolled250 locationsNCT06989112
Recruiting
Phase 3

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

IC-MPGN
Novartis Pharmaceuticals106 enrolled127 locationsNCT05755386
Recruiting
Phase 2

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Lupus Nephritis
Novartis Pharmaceuticals240 enrolled103 locationsNCT05268289
Recruiting
Phase 2

A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

Chagas Disease
Novartis Pharmaceuticals130 enrolled19 locationsNCT06632600
Recruiting
Phase 2

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

Stage IVB Prostate Cancer AJCC v8Metastatic Castration-Resistant Prostate Carcinoma
University of Washington51 enrolled3 locationsNCT06526299
Recruiting
Phase 3

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)

Hidradenitis Suppurativa
Novartis Pharmaceuticals555 enrolled145 locationsNCT06799000
Recruiting
Phase 3

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

Ovarian CancerFallopian Tube CancerPeritoneal Cancer
AbbVie520 enrolled264 locationsNCT05445778
Recruiting

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc.500 enrolled51 locationsNCT04202341
Recruiting
Not Applicable

Starting Technology in At Risk Type 1 Diabetes Study

Diabetes Mellitus, Type 1
University of California, Los Angeles40 enrolled3 locationsNCT06453928
Recruiting
Not Applicable

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

Venous InsufficiencyVenous Leg UlcerNon-infected Venous Leg Ulcer+2 more
BioStem Technologies60 enrolled23 locationsNCT06811909
Recruiting
Phase 2Phase 3

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism
AbbVie2,800 enrolled139 locationsNCT06345339
Recruiting
Phase 2

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

SuicideSuicidalSelf-harm
University of California, Los Angeles1,600 enrolled5 locationsNCT05304065
Recruiting
Not Applicable

Telehealth vs In-Person Evaluation of Addiction Treatment After Visiting the Emergency Department

Opioid-use Disorder
University of California, Davis528 enrolled3 locationsNCT06961058
Recruiting

Aveir VR Coverage With Evidence Development Post-Approval Study

ArrythmiaBradycardiaCardiac Pacemaker
Abbott Medical Devices8,744 enrolled1 locationNCT05336877
Recruiting
Not Applicable

Reducing Blood Pressure in Patients With High Cardiovascular Risk

HypertensionStrokeMyocardial Infarction
University of Southern California546 enrolled4 locationsNCT05937685
Recruiting

AVEIR DR Coverage With Evidence Development (CED) Study

ArrythmiaBradycardiaCardiac Pacemaker
Abbott Medical Devices2,812 enrolled1 locationNCT05932602
Recruiting

Aveir DR Real-World Evidence Post-Approval Study

ArrythmiaBradycardiaCardiac Pacemaker
Abbott Medical Devices1,805 enrolled1 locationNCT05935007
Recruiting

Aveir AR Coverage With Evidence Development (CED) Study

ArrhythmiaBradycardiaCardiac Pacemaker
Abbott Medical Devices586 enrolled1 locationNCT06100770
Recruiting

Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry

End Stage Renal Disease
LifeNet Health100 enrolled4 locationsNCT05880537
Recruiting

Aveir VR Real-World Evidence Post-Approval Study

ArrythmiaBradycardiaCardiac Pacemaker
Abbott Medical Devices2,100 enrolled1 locationNCT05270499