RecruitingPhase 2ACTRN12612000033842

The effects of yoghurt and its probiotics on features of the metabolic syndrome, intestinal function, bone metabolism and quality of life; a randomised controlled trial.

In elderly persons at risk of metabolic syndrome, is yoghurt and/or its probiotics efficacious at improving features of metabolic syndrome?


Sponsor

Professor Richard Prince

Enrollment

152 participants

Start Date

Feb 1, 2012

Study Type

Interventional

Conditions

Summary

This is a 6 week randomised controlled factorial study to evaluate the effects of yoghurt and its probiotics on risk of metabolic syndrome, quality of life, gastrointestinal health and bone metabolism.


Eligibility

Sex: Both males and femalesMin Age: 55 Yearss

Plain Language Summary

Simplified for easier understanding

This 6-week study tests whether eating yoghurt and taking probiotic supplements can improve components of metabolic syndrome — a cluster of conditions including high blood pressure, high blood sugar, abnormal cholesterol, and excess waist fat — as well as gut health, bone health, and quality of life. Metabolic syndrome increases the risk of heart disease and diabetes, and this study explores whether yoghurt/probiotics can help. You may be eligible if: - You are 55 years or older - You currently eat less than 400 g of yoghurt per week and do not take probiotic supplements - Your BMI is over 25 - Your waist circumference is over 94 cm (men) or 80 cm (women), OR your blood pressure is above 120/80 mmHg You may NOT be eligible if: - You are unlikely to complete the 6-week study - You cannot tolerate dairy foods - You are unable to attend the study centre for 4 visits over 9 weeks - You are currently taking antibiotics or immunosuppressant medications - You have type 2 diabetes requiring medication Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Arm 1: 200g/d Probiotic yoghurt consumed over a total of 6 weeks Arm 2: 3 x probiotic capsules/d consumed over a total of 6 weeks. Each capsule contains > 10 billion CFU probiotic bacteria

Arm 1: 200g/d Probiotic yoghurt consumed over a total of 6 weeks Arm 2: 3 x probiotic capsules/d consumed over a total of 6 weeks. Each capsule contains > 10 billion CFU probiotic bacteria


Locations(1)

Australia

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ACTRN12612000033842


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