A randomized clinical trial to determine the efficacy of Affron, a standardised extract of Saffron (Crocus sativus) on mood and cognitive function in healthy adults over 4 weeks.

This study is testing whether a saffron extract supplement called Affron can improve mood and mental sharpness in healthy adults who feel a bit down but have not been diagnosed with depression. Saffron is a spice that scientists believe may help with mood, memory, and sleep. Participants will take either Affron capsules or a look-alike sugar pill for 4 weeks, and researchers will check how their mood and thinking change. You may be eligible if: - You are between 16 and 75 years old - You sometimes feel low in mood but have NOT been diagnosed with depression - Your BMI is below 40 - You are willing to avoid foods cooked with saffron during the study You may NOT be eligible if: - You have been diagnosed with a mood disorder like depression or bipolar disorder - You take blood thinners such as warfarin - You take blood pressure medications - You have severe kidney or liver disease - You have a neurological disorder like multiple sclerosis - You work night shifts or suffer from insomnia - You are pregnant or currently in severe premenstrual pain Talk to your doctor about whether this trial might be right for you.