RecruitingACTRN12619000674134

Impact of patient position and intraabdominal gas used in laparoscopic hysterectomy on optic nerve sheath diameter which reflects intracranial pressure

Impact of pneumoperitoneum and patient position on optic nerve sheath diameter in laparoscopic hysterectomies.


Sponsor

University of Health Sciences

Enrollment

50 participants

Start Date

Mar 15, 2019

Study Type

Interventional

Conditions

Summary

We hypothesized that pneumoperitoneum and Trendelenburg position applied during laparoscopic hysterectomy would impact intracranial pressure. Optic nerve sheath diameter measured with USG reflects intracranial pressure. Therefore we are enrolling patients undergoing a laparoscopic hysterectomy in our institute and measuring optic nerve sheath diameter with a linear 13-6 megahertz probe during different stages of the surgery (eg. before and after pneumoperitoneum, before and after Trendelenburg position). The primary outcome is the change in optic nerve sheath diameter with pneumoperitoneum and Trendelenburg position. The secondary outcome is postoperative nausea and vomiting and postoperative headache.


Eligibility

Sex: FemalesMin Age: 38 YearssMax Age: 78 Yearss

Inclusion Criteria1

  • Female patients undergoing laparoscopic hysterectomy

Exclusion Criteria1

  • Patients with previous history of ocular disease, ocular surgery, neurologic disease and transient ischemic attack,

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Interventions

Optic nerve sheath diameter (ONSD) will be measured at six times using ultrasound : 1. Before anesthesia 2. 10 minutes after pneumoperitoneum 3. 10 minutes after Trendelenburg position 4. 60 min

Optic nerve sheath diameter (ONSD) will be measured at six times using ultrasound : 1. Before anesthesia 2. 10 minutes after pneumoperitoneum 3. 10 minutes after Trendelenburg position 4. 60 minutes after Trendelenburg position 5. 10 minutes after supine position 6.20 minutes after CO2 desufflation A laparoscopic hysterectomy will be carried out by the same surgeon who has over 10 years experience in gynecologic laparoscopy Anesthesia will be managed by the same anesthesiologists with 9 years experience ONSD measurement will be performed by a 15-year experienced radiologist.


Locations(1)

Istanbul, Turkey

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