RecruitingNCT02628314

Reliability of Pupil Response to Acute Pain


Sponsor

Wake Forest University Health Sciences

Enrollment

80 participants

Start Date

Aug 4, 2015

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this research study is to test whether researchers can reliably measure the response pupils have when an acute painful stimulus is experienced. Changes in the size of the pupil of the eye can be an indicator of brain activity in a region of the brain that is important for feeling pain.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • Adult (18-70)
  • Pain from hip or knee arthritis of moderate intensity
  • American Society of Anesthesiologists physical status 1-3

Exclusion Criteria7

  • Inability to complete study questionnaires
  • Pregnancy
  • Litigation or workers compensation related to hip or knee pain
  • Taking > 50 mg morphine equivalents/day
  • History of Raynaud's disease of the feet
  • Psychotic disorder or a recent psychiatric hospitalization
  • History of eye surgery or topical eye medications that would would directly affect pupil diameter

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Locations(1)

Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, United States

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NCT02628314


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