RecruitingPhase 1NCT02781519

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans


Sponsor

Yale University

Enrollment

100 participants

Start Date

Jun 1, 2015

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Inclusion Criteria2

  • at least one lifetime exposure to cannabis
  • good physical and mental health

Exclusion Criteria3

  • cannabis naive individuals
  • major current or recent stressors
  • taking estrogen supplements or oral contraceptive pills (for women)

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Interventions

DRUGTHC

Active THC (0.015mg/kg) administered over 10 minutes

DRUGPlacebo

Control: small amount of alcohol (quarter teaspoon), with no THC over 10 minutes


Locations(1)

Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine

West Haven, Connecticut, United States

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NCT02781519


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