Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis
Phenotypical Und Functional Characterization of Macrophages in Critically Ill Patients With Pseudomonas Aeruginosa Induced Sepsis
University of Ulm
100 participants
Aug 1, 2014
OBSERVATIONAL
Conditions
Summary
The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.
Eligibility
Inclusion Criteria3
- age \> 18 years
- critically ill patients with sepsis
- microbiologically proven infection with Pseudomonas aeruginosa
Exclusion Criteria2
- life expectancy \< 24 hours
- participation in other studies
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03044223