RecruitingNCT03044223

Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

Phenotypical Und Functional Characterization of Macrophages in Critically Ill Patients With Pseudomonas Aeruginosa Induced Sepsis

Sponsor

University of Ulm

Enrollment

100 participants

Start Date

Aug 1, 2014

Study Type

OBSERVATIONAL

Conditions

Sepsis Critically Ill Sepsis, Severe Pseudomonas Infections Pseudomonas Septicemia Pseudomonas; Pneumonia Pseudomonal Bacteraemia Pseudomonas Urinary Tract Infection Pseudomonas Gastrointestinal Tract Infection

Summary

The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.

Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with critically ill, pseudomonal bacteraemia, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Clinic of Anesthesiology

Ulm, Germany

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NCT03044223

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