RecruitingNot ApplicableNCT03452202

Using tDCS in Speech-based Stroke Rehabilitation


Sponsor

NYU Langone Health

Enrollment

24 participants

Start Date

Jan 11, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation. Transcranial direct current stimulation (tDCS), which delivers low-intensity current to the scalp, and is a safe and well-tolerated approach that poses a non-significant risk to participants. tDCS provides low intensity neural stimulation which has been shown to facilitate motor learning in other domains of stroke rehabilitation such as arm motor learning but the potential to enhance speech motor learning has not been explored. This will be examined with a series of single-case experimental designs.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether transcranial direct current stimulation (tDCS) — a gentle, non-invasive electrical brain stimulation technique — can improve speech rehabilitation for stroke survivors who have a condition called apraxia of speech. Apraxia of speech is a motor speech disorder where a person has difficulty planning and coordinating the precise movements needed to speak clearly, even though their muscles work fine and they know what they want to say. It is a common and often frustrating outcome of strokes that affect the left side of the brain. tDCS uses a mild electrical current delivered through electrodes placed on the scalp. It does not cause pain and is thought to enhance the brain's responsiveness to therapy. In this study, tDCS will be combined with speech therapy to see if it speeds up or improves recovery compared to speech therapy alone. You may be eligible if: - You are 18 years old or older - You are right-handed - You speak English only (monolingual) - You had a single stroke in the left hemisphere of your brain - It has been at least 6 months since your stroke - You have been clinically diagnosed with apraxia of speech - You have normal speech perception and passing hearing You may NOT be eligible if: - You have a voice disorder of the larynx (voice box) - You have dysarthria (weakness-related speech problems) - You had speech problems before your stroke - You have a pacemaker or any electrically/magnetically activated implant - You have metal anywhere in your body - You have a family history of medication-resistant epilepsy - You have a personal history of seizures or unexplained loss of consciousness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICESoterix 1x1 line tDCS low-intensity stimulator

Introduction of the independent variable (treatment) across three different points in time. Participants will be randomly assigned to have each treatment phase begin after 3, 4, or 6 baseline sessions. This current stimulates the cortex, with anodal stimulation leading to a depolarized state in which neurons are more likely to fire.

DEVICESham

Patients will have two electrodes applied (one anode, one cathode) administering no stimulation


Locations(2)

New York University School of Medicine

New York, New York, United States

Burke Rehabilitation Hospital

White Plains, New York, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03452202


Related Trials