RecruitingNot ApplicableNCT03452202

Using tDCS in Speech-based Stroke Rehabilitation


Sponsor

NYU Langone Health

Enrollment

24 participants

Start Date

Jan 11, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation. Transcranial direct current stimulation (tDCS), which delivers low-intensity current to the scalp, and is a safe and well-tolerated approach that poses a non-significant risk to participants. tDCS provides low intensity neural stimulation which has been shown to facilitate motor learning in other domains of stroke rehabilitation such as arm motor learning but the potential to enhance speech motor learning has not been explored. This will be examined with a series of single-case experimental designs.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria7

  • Right-handed
  • Monolingual (English)
  • Single left-hemisphere CVA
  • A minimum of six months post-stroke
  • Clinical diagnosis of apraxia of speech
  • Normal speech perception
  • Passing score on the hearing screening.

Exclusion Criteria8

  • Diagnosis of laryngeal voice disorder
  • Dysarthria
  • History of speech impairment prior to CVA
  • Presence of potential tDCS risk factors: damaged skin at site of stimulation;
  • Presence of electrically or magnetically activated implant (including pacemaker);
  • metal in any part of their body;
  • history of medication-resistant epilepsy in the family;
  • past history of seizures or unexplained spells of loss of consciousness.

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Interventions

DEVICESoterix 1x1 line tDCS low-intensity stimulator

Introduction of the independent variable (treatment) across three different points in time. Participants will be randomly assigned to have each treatment phase begin after 3, 4, or 6 baseline sessions. This current stimulates the cortex, with anodal stimulation leading to a depolarized state in which neurons are more likely to fire.

DEVICESham

Patients will have two electrodes applied (one anode, one cathode) administering no stimulation


Locations(2)

New York University School of Medicine

New York, New York, United States

Burke Rehabilitation Hospital

White Plains, New York, United States

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NCT03452202


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