RecruitingNot ApplicableNCT04604444

Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech

Evaluating the Effects of Intensive Speech and Language Rehabilitation Regarding Neuroplasticity, Speech, Language, Communication Skills and Quality of Life for People With Acquired Aphasia and/or Apraxia of Speech in the Chronic Phase


Sponsor

Karolinska Institutet

Enrollment

30 participants

Start Date

Feb 2, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural correlates in thirty persons with chronic stroke. Changes are studied following intensive treatment of aphasia and AOS with standardised speech-language testing and testing of communication and with voxel-based morphometry (VBM) analysis and resting state functional connectivity (rsFC).


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria2

  • Aphasia 7 months post stroke diagnosed by SLP
  • Apraxia of Speech 7 months post stroke diagnosed by SLP

Exclusion Criteria5

  • Dementia
  • Severe loss of sight
  • Severe loss of hearing
  • Metal implants (preventing fMRI)
  • Claustrophobia (preventing fMRI)

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Interventions

BEHAVIORALMultimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech

Intensive Comprehensive Aphasia (ICAP) and Apraxia of Speech Program


Locations(1)

Uppsala Universitet

Uppsala, Sweden

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NCT04604444


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