RecruitingNot ApplicableNCT03481205
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
Sponsor
Enrique Leira
Enrollment
10 participants
Start Date
Jun 1, 2020
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic stroke due to large vessel occlusion being transported to a thrombectomy capable center by the helicopter.
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria5
- Age ≥18 and ≤ 80 years
- Suspected acute ischemic stroke with symptoms suggestive of large vessel occlusion (aphasia, agnosia, neglect, visual field cut, and gaze preference).
- Patient screened for rtPA, and rtPA administered if eligible
- Subject or legally authorized representative able to provide consent at the time of the assessment
- NIHSS 6-20
Exclusion Criteria8
- Any intracranial hemorrhage (parenchymal, subarachnoid, subdural, epidural) on CT scan at the community hospital
- History of upper or lower extremity ischemia, known subclavian, brachial artery, iliac or femoral artery stenosis, subclavian steal syndrome, any upper or lower extremity soft tissue, orthopedic or vascular injury, or mastectomy or other procedure that may contraindicate taking blood pressure or having a cuff on the arm or leg for the conditioning treatment
- History of diabetes mellitus
- Enrollment in another clinical trial
- Patient incarcerated
- Pregnancy. Patients ages 18-55 will need to have a negative urine or blood based pregnancy test.
- Agitation deemed unsafe for ischemic preconditioning testing.
- Arteriovenous fistula in upper limb
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
DEVICEIschemic conditioning device
RLIC will be done using a specialized blood pressure device ( Doctormate) that inflates to 200 mm HG for 5 minutes followed by 5 minutes deflation.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03481205
Related Trials
Continuous Dual Aspiration Technique With Zoom System for Stroke
NCT074919529 locations
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
NCT0506521666 locations
Sensory-Motor Rehabilitation Post Stroke
NCT023697701 location
Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)
NCT041756911 location
Non-immunogenic Staphylokinase in Reperfusion Therapy of Ischemic Stroke in Routine Clinical Practice
NCT056975751 location