RecruitingNCT03657745

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

An Observational Trial of Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Sponsor

Alzheimer's Light LLC

Enrollment

2,000 participants

Start Date

Jan 1, 2018

Study Type

OBSERVATIONAL

Conditions

Dementia Cognitive Decline Alzheimer Disease Mild Cognitive Impairment Cognition Disorders in Old Age Cognitive Deterioration

Summary

Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https://www.alz.life/) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.

Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether combining light therapy (flickering at 40 times per second) with memory and thinking exercises (cognitive therapy) can improve symptoms in people with Alzheimer's disease. **You may be eligible if...** - You have been diagnosed with Alzheimer's disease - You have measurable problems with memory or thinking (cognitive impairment) - You are able to undergo light-based therapy through your eyes **You may NOT be eligible if...** - You have ever had an epileptic seizure, including childhood febrile (fever-related) seizures, because flickering light can trigger seizures - You have a significant eye disease (such as macular degeneration) that would prevent you from receiving light therapy - You are taking medications that lower the seizure threshold - You are unable to cooperate with the therapy sessions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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