RecruitingNCT03667027
Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant
Sponsor
University Health Network, Toronto
Enrollment
40 participants
Start Date
Apr 1, 2019
Study Type
OBSERVATIONAL
Conditions
Summary
This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Receiving a respiratory support modality as a bridge to lung transplantation
- Formally listed for transplantation
- \- Undergoing lung transplantation for either obstructive or restrictive lung disease
- \- Undergoing elective thoracic surgery without any prior history of chronic pulmonary parenchymal disease
Exclusion Criteria3
- Previously diagnosed with neuromuscular disorder
- Received invasive mechanical ventilation for >48 hours in the preceding four weeks
- Thoracic cage deformity
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Interventions
DEVICERespiratory support
Mechanical ventilation or extracorporeal life support
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03667027
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