Mechanical Ventilation Complication Clinical Trials

30 recruitingLast updated: June 17, 2026

There are 30 actively recruiting mechanical ventilation complication clinical trials across 16 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Beijing, Beijing Municipality, China, Iowa City, Iowa, United States, Columbus, Ohio, United States. Updated daily from ClinicalTrials.gov.


Mechanical Ventilation Complication Trials at a Glance

30 actively recruiting trials for mechanical ventilation complication are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Beijing, Iowa City, and Columbus. Lead sponsors running mechanical ventilation complication studies include University Health Network, Toronto, Australian and New Zealand Intensive Care Research Centre, and Assiut University.

Browse mechanical ventilation complication trials by phase

Treatments under study

About Mechanical Ventilation Complication Clinical Trials

Looking for clinical trials for Mechanical Ventilation Complication? There are currently 30 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mechanical Ventilation Complication trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mechanical Ventilation Complication clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting
Not Applicable

Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation

Mechanical Ventilation ComplicationAcute Hypoxemic Respiratory Failure
Centre for Medical Sciences36 enrolled1 locationNCT06921655
Recruiting
Phase 2Phase 3

Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome

Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeSedation Complication
Guy's and St Thomas' NHS Foundation Trust20 enrolled1 locationNCT06014138
Recruiting
Not Applicable

Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)

Mechanical Ventilation ComplicationPulmonary Edema
Centre Hospitalier Universitaire de Nice250 enrolled3 locationsNCT05226247
Recruiting
Not Applicable

Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ventilation

Mechanical Ventilation ComplicationMucus Retention
Hospital Clinic of Barcelona26 enrolled1 locationNCT06491017
Recruiting
Not Applicable

Behavioral Economic & Staffing Strategies in the ICU

ICU acquired weaknessPainMechanical Ventilation Complication+3 more
University of Nebraska8,100 enrolled3 locationsNCT06184945
Recruiting

Diaphragm Atrophy and Dysfunction in Mechanical Ventilation

Respiratory FailureMechanical Ventilation ComplicationIntensive Care (ICU) Myopathy+1 more
RWTH Aachen University15 enrolled1 locationNCT05211661
Recruiting
Phase 4

Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients

SurgeryMechanical Ventilation ComplicationCritical Illness+3 more
Beijing Shijitan Hospital, Capital Medical University306 enrolled1 locationNCT06575530
Recruiting
Not Applicable

The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery

Gynecologic CancerAnesthesiaMechanical Ventilation Complication
Umraniye Education and Research Hospital120 enrolled1 locationNCT06482983
Recruiting
Not Applicable

EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery

ObesityMechanical Ventilation ComplicationRecruitment+2 more
Jianbo Wu118 enrolled1 locationNCT07207772
Recruiting

Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units

Mechanical Ventilation ComplicationPain Intensity AssessmentSedation and Analgesia
Centro Universitário Augusto Motta370 enrolled4 locationsNCT07182851
Recruiting

A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

ventilator-induced lung injuryMechanical Ventilation Complication
Centre hospitalier de l'Université de Montréal (CHUM)10 enrolled1 locationNCT03405779
Recruiting
Not Applicable

VentilO Prospective Study

Mechanical Ventilation ComplicationRespiratory Acidosis
Laval University76 enrolled1 locationNCT06826794
Recruiting
Not Applicable

Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study

Mechanical Ventilation ComplicationOral Bacterial Infection
The Cleveland Clinic21 enrolled1 locationNCT06193512
Recruiting

Early Diagnosis of ARDS in Mechanically Ventilated Patient Using LUS Score in Comparison With CT

Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeComputed Tomography
Tanta University20 enrolled1 locationNCT06971042
Recruiting
Not Applicable

Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

Mechanical Ventilation Complication
University of Chicago468 enrolled2 locationsNCT03901924
Recruiting
Not Applicable

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Respiratory FailureMechanical Ventilation ComplicationLung Injury+2 more
Siriraj Hospital214 enrolled1 locationNCT06203405
Recruiting

Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia

Mechanical Ventilation ComplicationPediatric ALLPulmonary Complication+1 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)10,000 enrolled4 locationsNCT06166706
Recruiting
Phase 4

The Caffeine Therapy in the Fetal to Neonatal Transition

Mechanical Ventilation ComplicationVentilator Lung; NewbornCaffeine
Hospital de Clinicas de Porto Alegre50 enrolled1 locationNCT05454332
Recruiting
Not Applicable

How Early Mobilization Impacts on Diaphragm Thickness in Critically Ill Children

Mechanical Ventilation ComplicationVentilator-induced Diaphragm Dysfunction
Children's Hospital of Fudan University160 enrolled1 locationNCT04534296
Recruiting
Not Applicable

NMES Role to Prevent Respiratory Muscle Weakness in Critically Ill Patients and Its Association to Changes in Myokines.

Mechanical Ventilation ComplicationMuscle Weakness or AtrophyElectrical Stimulations
Pontificia Universidad Catolica de Chile32 enrolled1 locationNCT05536531