RecruitingNCT03753412

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

Prospective Observational Study Regarding the Determinants of Functional Disability and Quality of Life in Patients Recovering From Severe Acute Cardiac or Respiratory Failure Considered for Mechanical Cardiorespiratory Support (CLEVERER)

Sponsor

Barts & The London NHS Trust

Enrollment

100 participants

Start Date

Apr 9, 2019

Study Type

OBSERVATIONAL

Conditions

Respiratory Failure Cardiac Failure Acute Respiratory Distress Syndrome Intensive Care Unit Syndrome Intensive Care Neuropathy Intensive Care (ICU) Myopathy Critical Illness Myopathy

Summary

To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying the recovery process for adults who experience severe muscle weakness after surviving severe heart and lung failure that required a life-support machine called ECMO (a machine that temporarily does the work of the heart and lungs). **You may be eligible if...** - You are 18 years or older - You have had severe heart and/or lung failure requiring ECMO life support - You or a representative on your behalf has agreed to participate in the trial **You may NOT be eligible if...** - You have previously had a stroke - You have an underlying neuromuscular disease (such as muscular dystrophy or ALS) - You have cancer - You are under 18 years of age Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

St Bartholomew's hospital (Barts NHS trust)

London, United Kingdom

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NCT03753412

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