Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium

This study compares a new eye imaging dye called MB-102 to the standard dye fluorescein sodium, which is commonly used in a procedure called ocular angiography to visualize blood vessels in the eye. Doctors use these dyes to diagnose and monitor conditions like macular degeneration and diabetic eye disease. The study is testing whether MB-102 is a safe and effective alternative. Fluorescein sodium has been used for decades but can sometimes cause side effects. MB-102 is a newer compound that researchers believe may work similarly with a potentially improved safety profile. This study compares image quality and safety between the two dyes in adult patients. **You may be eligible if...** - You are 18 years of age or older - You are willing to comply with study requirements and have signed informed consent - If female, you are either not of childbearing potential or are using adequate contraception - If male, you are willing to use contraception or abstain for 7 days after the dose **You may NOT be eligible if...** - You are pregnant, breastfeeding, or planning to become pregnant - You have had a prior allergic reaction or anaphylaxis to MB-102, fluorescein, or similar substances - You have a history of seizures - You have participated in another interventional trial within 30 days - You have a history of drug or alcohol abuse within the past year - You have significant cataracts or other eye conditions that would interfere with photography **Talk to your doctor** about your eye health history, any allergy history, and whether you are a good candidate for this imaging procedure comparison.