RecruitingNot ApplicableNCT04041154

Behavioral and Neural Representations of Subjective Effort Cost


Sponsor

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Enrollment

185 participants

Start Date

Aug 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.


Eligibility

Min Age: 18 YearsMax Age: 35 Years

Inclusion Criteria3

  • Right-handed
  • Age between 18 and 35 years old - Male or female
  • Any ethnicity

Exclusion Criteria6

  • Individuals with a history of any of the following will be excluded from the study:
  • Neurological problems such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease (self- report)
  • Diagnosed history of severe psychiatric disease such as depression, schizophrenia (self-report)
  • Metal in the head or eyes
  • If they are pregnant or suspect that you may be pregnant
  • If they experience discomfort from the MRI scan, such as severe claustrophobia or excessive heating of tattoos

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Interventions

BEHAVIORALCognitive Fatigue

Participants will perform a cognitively demanding task (spatial attention task), repeatedly, to induce cognitive fatigue.

BEHAVIORALPhysical Fatigue

Participants will perform a physically demanding task (grip force exertion task), repeatedly, to induce cognitive fatigue.

BEHAVIORALRewarding Stimuli

Reward-associated stimuli will be used to study how reward-induced changes in motivational state influence effort choices.


Locations(1)

Kennedy Krieger Institute

Baltimore, Maryland, United States

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NCT04041154


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