Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue.
Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study
VA Office of Research and Development
60 participants
Apr 10, 2023
INTERVENTIONAL
Conditions
Summary
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.
Eligibility
Inclusion Criteria3
- - 80 years of age
- more than 6 months post-stroke
- Clinically present fatigue
Exclusion Criteria7
- Contraindications to MRI/TMS/rTMS (e.g. implanted metal within the head, history of seizures)
- Inability to follow simple three-step instructions
- Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe TBI)
- Pregnancy
- strokes within stimulation sites
- Pregnancy
- Severe hypertension (resting SBP > 200, DBP > 120)
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Interventions
MagVenture MagPro X100 with MagOption
MagVenture MagPro X100 with MagOption
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05584124