Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans
University of Delaware
90 participants
Jan 16, 2020
INTERVENTIONAL
Conditions
Summary
Americans continue to consume high amounts of sodium. Potassium is notable for its blood pressure lowering effects but less is known regarding its effect on the vasculature. This investigation seeks to determine the role of dietary potassium on the vasculature in the presence of a high sodium diet in salt-resistant adults.
Eligibility
Inclusion Criteria3
- healthy
- normal blood pressure
- normal resting ECG
Exclusion Criteria11
- hypertension
- history of heart disease
- diabetes
- kidney disease
- obese (BMI ≥30)
- significant weight changes in the last 6 months
- use of tobacco products
- pregnant
- on a special diet (gluten free; vegan)
- take any medications for the above conditions
- endurance trained athletes
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Interventions
Consumption of 10 days of a diet moderate in potassium and low in sodium.
Consumption of 10 days of a diet moderate in potassium and high in sodium.
Consumption of 10 days of a diet high in potassium and high in sodium.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04101188