RecruitingNot ApplicableNCT04137133

Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicine

Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicine.Descriptive Monocentric Study for Identification and Validation of Biomarkers Predictive of Clinical Evolution


Sponsor

University Hospital, Brest

Enrollment

20 participants

Start Date

Mar 21, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to evaluate the relevance of Porphyromonas as a biomarker predicting the risk of P. aeruginosa primocolonization in children form 0 to 18 years old with cystic fibrosis.


Eligibility

Max Age: 18 Years

Inclusion Criteria4

  • Newly screened infants with a confirmed diagnosis of cystic fibrosis in its classic form (clinical symptoms and two positive sweat tests and/or two mutations of the cftr gene from Class I to III)
  • Children free of any colonization with P. aeruginosa
  • Affiliation with the social security system
  • Consent signed by the holders of parental authority or the sole parent holding parental authority

Exclusion Criteria6

  • Children colonized with P. aeruginosa according to the cytobacteriological examination and / or molecular test of sputum or pharyngeal specimens
  • Children grafted
  • Children not affiliated to a social security scheme or not entitled to
  • Children whose parent (s) are (are) minor (s)
  • Children whose holders of parental authority do not master the French language
  • Refusal to participate in the study

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Interventions

DIAGNOSTIC_TESTcollection

bronchial secretions, blood, stools, superficial skin sample, dental plaque sample and urine


Locations(1)

Fondation Ildys

Roscoff, France

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NCT04137133


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