Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study

This study is using specialized PET imaging (PSMA or FACBC scans) to find exactly where prostate cancer has returned after surgery and radiation, and then directing targeted radiation treatment to those specific spots — rather than treating the whole body. **You may be eligible if...** - You have prostate adenocarcinoma (confirmed by biopsy) - You have already had your prostate removed (radical prostatectomy) - You have already had radiation to the prostate area (as adjuvant or salvage treatment) - Your PSA (prostate specific antigen) level is between 0.2 and 10 ng/mL, indicating cancer recurrence **You may NOT be eligible if...** - You have already received systemic therapy (e.g., hormone therapy) for this recurrence - You have evidence of distant metastases (cancer spread beyond the pelvis) - You are unable to undergo radiation therapy for medical reasons Talk to your doctor to see if this trial is right for you.