RecruitingNCT04318119

Cerebral Small Vessel Disease Registry Study


Sponsor

Bin Cai

Enrollment

3,000 participants

Start Date

Nov 18, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Small Vessel Disease (CSVD) and in a prospective multicenter study, to assess the clinical, genetic and epigenetic features of patients with CSVD, , to find independent imaging markers, and to optimize clinical management.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria3

  • Sign informed consent.
  • Age\>18
  • At least one of the following CSVD MRI characteristics: ①recent small subcortical infarct;②lacune of presumed vascular origin;③white matter hypertensity of presumed vascular origin;④perivascular space;⑤cerebral microbleeds;⑥brain atrophy

Exclusion Criteria5

  • Unable to cooperate with inspectors
  • Non-vascular white matter lesions
  • Other cognitive diseases (such as alzheimer's disease, Parkinson's disease or thyroid disease)
  • Serious systemic illness, such as heart, liver, kidney disease or major mental illness
  • Contraindications for imaging examination

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Locations(1)

Department of Neurology , First Affiliated Hospital Fujian Medical University

Fuzhou, Fujian, China

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NCT04318119


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